Assembly, analysis and architecture of atypical ubiquitin chains

por Hospenthal, Manuela K., Freund, Stefan M.V., Komander, David
Publicado 2013

GpIbα Interacts Exclusively with Exosite II of Thrombin()

por Lechtenberg, Bernhard C., Freund, Stefan M.V., Huntington, James A.
Publicado 2014

The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis

por Allen, Mark D., Freund, Stefan M.V., Zinzalla, Giovanna, Bycroft, Mark
Publicado 2015

SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site

por Allen, Mark D., Freund, Stefan M. V., Bycroft, Mark, Zinzalla, Giovanna
Publicado 2021

Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core

por Khoo, Kian Hoe, Joerger, Andreas C., Freund, Stefan M.V., Fersht, Alan R.
Publicado 2009

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

por Rajagopalan, Sridharan, Andreeva, Antonina, Teufel, Daniel P., Freund, Stefan M., Fersht, Alan R.
Publicado 2009

High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1

por Jacobsen, Julian O. B., Allen, Mark D., Freund, Stefan M. V., Bycroft, Mark
Publicado 2016

Molecular Basis for Modulation of the p53 Target Selectivity by KLF4

por Brandt, Tobias, Townsley, Fiona M., Teufel, Daniel P., Freund, Stefan M. V., Veprintsev, Dmitry B.
Publicado 2012

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

por Gersch, Malte, Wagstaff, Jane L., Toms, Angela V., Graves, Bradford, Freund, Stefan M.V., Komander, David
Publicado 2019

Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA

por Sammak, Susan, Hamdani, Najoua, Gorrec, Fabrice, Allen, Mark D., Freund, Stefan M. V., Bycroft, Mark, Zinzalla, Giovanna
Publicado 2019

Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53

por Wong, Tuck Seng, Rajagopalan, Sridharan, Townsley, Fiona M., Freund, Stefan M., Petrovich, Miriana, Loakes, David, Fersht, Alan R.
Publicado 2009

Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites

por Beitia, Gonzalo J., Rutherford, Trevor J., Freund, Stefan M. V., Pelham, Hugh R., Bienz, Mariann, Gammons, Melissa V.
Publicado 2021

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid

por de la Roche, Marc, Rutherford, Trevor J., Gupta, Deepti, Veprintsev, Dmitry B., Saxty, Barbara, Freund, Stefan M., Bienz, Mariann
Publicado 2012

Dynamics in Fip1 regulate eukaryotic mRNA 3′ end processing

por Kumar, Ananthanarayanan, Yu, Conny W.H., Rodríguez-Molina, Juan B., Li, Xiao-Han, Freund, Stefan M.V., Passmore, Lori A.
Publicado 2021

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

por Wong, Tuck Seng, Rajagopalan, Sridharan, Freund, Stefan M., Rutherford, Trevor J., Andreeva, Antonina, Townsley, Fiona M., Petrovich, Miriana, Fersht, Alan R.
Publicado 2009

Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer

por Natan, Eviatar, Baloglu, Cetin, Pagel, Kevin, Freund, Stefan M.V., Morgner, Nina, Robinson, Carol V., Fersht, Alan R., Joerger, Andreas C.
Publicado 2011

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

por Allen, Mark D., Christie, Mary, Jones, Peter, Porebski, Benjamin T., Roome, Brendan, Freund, Stefan M.V., Buckle, Ashley M., Bycroft, Mark, Christ, Daniel
Publicado 2015

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C

por Ho, Anita K., Wagstaff, Jane L., Manna, Paul T., Wartosch, Lena, Qamar, Seema, Garman, Elspeth F., Freund, Stefan M. V., Roberts, Rhys C.
Publicado 2016

Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis

por Joseph, Nimesh, Al-Jassar, Caezar, Johnson, Christopher M., Andreeva, Antonina, Barnabas, Deepak D., Freund, Stefan M.V., Gergely, Fanni, van Breugel, Mark
Publicado 2018

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

por von Muhlinen, Natalia, Akutsu, Masato, Ravenhill, Benjamin J., Foeglein, Ágnes, Bloor, Stuart, Rutherford, Trevor J., Freund, Stefan M.V., Komander, David, Randow, Felix
Publicado 2012