CD8(+) memory T-cell inflation renders compromised CD4(+) T-cell-dependent CD8(+) T-cell immunity via naïve T-cell anergy

por Xu, Aizhang, Freywald, Andrew, Xie, Yufeng, Li, Zejun, Xiang, Jim
Publicado 2017

Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia

por K. Bhanumathy, Kalpana, Balagopal, Amrutha, Vizeacoumar, Frederick S., Vizeacoumar, Franco J., Freywald, Andrew, Giambra, Vincenzo
Publicado 2021

Structure of the EphB6 receptor ectodomain

por Mason, Emilia O., Goldgur, Yehuda, Robev, Dorothea, Freywald, Andrew, Nikolov, Dimitar B., Himanen, Juha P.
Publicado 2021

CD154 and IL-2 Signaling of CD4(+) T Cells Play a Critical Role in Multiple Phases of CD8(+) CTL Responses Following Adenovirus Vaccination

por Sokke Umeshappa, Channakeshava, Hebbandi Nanjundappa, Roopa, Xie, Yufeng, Freywald, Andrew, Deng, Yulin, Ma, Hong, Xiang, Jim
Publicado 2012

The CINs of Polo-Like Kinase 1 in Cancer

por Cunningham, Chelsea E., MacAuley, Mackenzie J., Vizeacoumar, Frederick S., Abuhussein, Omar, Freywald, Andrew, Vizeacoumar, Franco J.
Publicado 2020

The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment

por El Zawily, Amr, McEwen, Emily, Toosi, Behzad, Vizeacoumar, Frederick S., Freywald, Tanya, Vizeacoumar, Franco J., Freywald, Andrew
Publicado 2017

Th Cells Promote CTL Survival and Memory via Acquired pMHC-I and Endogenous IL-2 and CD40L Signaling and by Modulating Apoptosis-Controlling Pathways

por Umeshappa, Channakeshava Sokke, Xie, Yufeng, Xu, Shulin, Nanjundappa, Roopa Hebbandi, Freywald, Andrew, Deng, Yulin, Ma, Hong, Xiang, Jim
Publicado 2013

IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia

por Xu, Aizhang, Bhanumathy, Kalpana Kalyanasundaram, Wu, Jie, Ye, Zhenmin, Freywald, Andrew, Leary, Scot C., Li, Rongxiu, Xiang, Jim
Publicado 2016

Mining the plasma-proteome associated genes in patients with gastro-esophageal cancers for biomarker discovery

por Vizeacoumar, Frederick S., Guo, Hongyu, Dwernychuk, Lynn, Zaidi, Adnan, Freywald, Andrew, Wu, Fang-Xiang, Vizeacoumar, Franco J., Ahmed, Shahid
Publicado 2021

Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy

por Arna, Ananna Bhadra, Patel, Hardikkumar, Singh, Ravi Shankar, Vizeacoumar, Frederick S., Kusalik, Anthony, Freywald, Andrew, Vizeacoumar, Franco J., Wu, Yuliang
Publicado 2023

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation

por El Zawily, Amr M., Toosi, Behzad M., Freywald, Tanya, Indukuri, Vijaya V., Vizeacoumar, Franco J., Leary, Scot C., Freywald, Andrew
Publicado 2016

Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways

por Tan, Xin, Xu, Aizhang, Zhao, Tuo, Zhao, Qin, Zhang, Jun, Fan, Cuihong, Deng, Yulin, Freywald, Andrew, Genth, Harald, Xiang, Jim
Publicado 2018

Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability

por Jing, Anqi, Vizeacoumar, Frederick S., Parameswaran, Sreejit, Haave, Bjorn, Cunningham, Chelsea E., Wu, Yuliang, Arnold, Roland, Bonham, Keith, Freywald, Andrew, Han, Jie, Vizeacoumar, Franco J.
Publicado 2018

A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers

por Elhasasna, Hussain, Khan, Raymond, Bhanumathy, Kalpana K., Vizeacoumar, Frederick S., Walke, Prachi, Bautista, Maricris, Dahiya, Dinesh K., Maranda, Vincent, Patel, Hardikkumar, Balagopal, Amrutha, Alli, Nezeka, Krishnan, Anand, Freywald, Andrew, Vizeacoumar, Franco J.
Publicado 2022

An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer

por Auslander, Noam, Cunningham, Chelsea E, Toosi, Behzad M, McEwen, Emily J, Yizhak, Keren, Vizeacoumar, Frederick S, Parameswaran, Sreejit, Gonen, Nir, Freywald, Tanya, Bhanumathy, Kalpana K, Freywald, Andrew, Vizeacoumar, Franco J, Ruppin, Eytan
Publicado 2017

Identification of novel genes involved in apoptosis of HIV-infected macrophages using unbiased genome-wide screening

por Dong, Simon X. M., Vizeacoumar, Frederick S., Bhanumathy, Kalpana K., Alli, Nezeka, Gonzalez-Lopez, Cristina, Gajanayaka, Niranjala, Caballero, Ramon, Ali, Hamza, Freywald, Andrew, Cassol, Edana, Angel, Jonathan B., Vizeacoumar, Franco J., Kumar, Ashok
Publicado 2021

Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment

por Paul, James M., Toosi, Behzad, Vizeacoumar, Frederick S., Bhanumathy, Kalpana Kalyanasundaram, Li, Yue, Gerger, Courtney, Zawily, Amr El, Freywald, Tanya, Anderson, Deborah H., Mousseau, Darrell, Kanthan, Rani, Zhang, Zhaolei, Vizeacoumar, Franco J., Freywald, Andrew
Publicado 2016

Glycosylation States of Pre- and Post-synaptic Markers of 5-HT Neurons Differ With Sex and 5-HTTLPR Genotype in Cortical Autopsy Samples

por Nyarko, Jennifer N. K., Quartey, Maa O., Heistad, Ryan M., Pennington, Paul R., Poon, Lisa J., Knudsen, Kaeli J., Allonby, Odette, El Zawily, Amr M., Freywald, Andrew, Rauw, Gail, Baker, Glen B., Mousseau, Darrell D.
Publicado 2018

Molecular characterization of an MLL1 fusion and its role in chromosomal instability

por Parameswaran, Sreejit, Vizeacoumar, Frederick S., Kalyanasundaram Bhanumathy, Kalpana, Qin, Fujun, Islam, Md. Fahmid, Toosi, Behzad M., Cunningham, Chelsea E., Mousseau, Darrell D., Uppalapati, Maruti C., Stirling, Peter C., Wu, Yuliang, Bonham, Keith, Freywald, Andrew, Li, Hui, Vizeacoumar, Franco J.
Publicado 2018

EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours

por Toosi, Behzad M., El Zawily, Amr, Truitt, Luke, Shannon, Matthew, Allonby, Odette, Babu, Mohan, DeCoteau, John, Mousseau, Darrell, Ali, Mohsin, Freywald, Tanya, Gall, Amanda, Vizeacoumar, Frederick S., Kirzinger, Morgan W., Geyer, C. Ronald, Anderson, Deborah H., Kim, TaeHyung, Welm, Alana L., Siegel, Peter, Vizeacoumar, Franco J., Kusalik, Anthony, Freywald, Andrew
Publicado 2018