Ruthenium Complex HB324 Induces Apoptosis via Mitochondrial Pathway with an Upregulation of Harakiri and Overcomes Cisplatin Resistance in Neuroblastoma Cells In Vitro

por Wilke, Nicola L., Burmeister, Hilke, Frias, Corazon, Ott, Ingo, Prokop, Aram
Publicado 2023

A metal-free salalen ligand with anti-tumor and synergistic activity in resistant leukemia and solid tumor cells via mitochondrial pathway

por Hopff, Sina M., Wang, Qifang, Frias, Corazon, Ahrweiler, Marie, Wilke, Nicola, Wilke, Nathalie, Berkessel, Albrecht, Prokop, Aram
Publicado 2021

Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytosta...

por Baas, Jennifer, Bieringer, Sebastian, Frias, Corazon, Frias, Jerico, Soehnchen, Carolina, Urmann, Corinna, Ritter, Steffi, Riepl, Herbert, Prokop, Aram
Publicado 2022

An organometallic analogue of combretastatin A-4 and its apoptosis-inducing effects on lymphoma, leukemia and other tumor cells in vitro

por Abodo Onambele, Liliane, Hoffmann, Natalie, Kater, Lisa, Hemmersbach, Lars, Neudörfl, Jörg-Martin, Sitnikov, Nikolay, Kater, Benjamin, Frias, Corazon, Schmalz, Hans-Günther, Prokop, Aram
Publicado 2022

Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden

por Prinz, Christian, Vasyutina, Elena, Lohmann, Gregor, Schrader, Alexandra, Romanski, Steffen, Hirschhäuser, Christoph, Mayer, Petra, Frias, Corazon, Herling, Carmen D., Hallek, Michael, Schmalz, Hans-Günther, Prokop, Aram, Mougiakakos, Dimitrios, Herling, Marco
Publicado 2015

B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner

por Stein, Andreas, Hilken née Thomopoulou, Persefoni, Frias, Corazon, Hopff, Sina M., Varela, Paloma, Wilke, Nicola, Mariappan, Arul, Neudörfl, Jörg-Martin, Fedorov, Alexey Yu, Gopalakrishnan, Jay, Gigant, Benoît, Prokop, Aram, Schmalz, Hans-Günther
Publicado 2022