Obesity, POMC, and POMC-processing Enzymes: Surprising Results From Animal Models

por Lindberg, Iris, Fricker, Lloyd D
Publicado 2021

ProSAAS-Derived Peptides Are Differentially Processed and Sorted in Mouse Brain and AtT-20 Cells

por Wardman, Jonathan H., Fricker, Lloyd D.
Publicado 2014

Carboxypeptidase A6 in Zebrafish Development and Implications for VIth Cranial Nerve Pathfinding

por Lyons, Peter J., Ma, Leung-hang, Baker, Robert, Fricker, Lloyd D.
Publicado 2010

Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules

por Lopes, Mark William, Sapio, Matthew R., Leal, Rodrigo B., Fricker, Lloyd D.
Publicado 2016

ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake

por Wardman, Jonathan H., Berezniuk, Iryna, Di, Shi, Tasker, Jeffrey G., Fricker, Lloyd D.
Publicado 2011

Novel Carboxypeptidase A6 (CPA6) Mutations Identified in Patients with Juvenile Myoclonic and Generalized Epilepsy

por Sapio, Matthew R., Vessaz, Monique, Thomas, Pierre, Genton, Pierre, Fricker, Lloyd D., Salzmann, Annick
Publicado 2015

Proteasome Inhibitors Alter Levels of Intracellular Peptides in HEK293T and SH-SY5Y Cells

por Dasgupta, Sayani, Castro, Leandro M., Dulman, Russell, Yang, Ciyu, Schmidt, Marion, Ferro, Emer S., Fricker, Lloyd D.
Publicado 2014

Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells

por Dasgupta, Sayani, Fishman, Michael A., Castro, Leandro M., Tashima, Alexandre K., Ferro, Emer S., Fricker, Lloyd D.
Publicado 2019

Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington’s Disease

por Dasgupta, Sayani, Fishman, Michael A., Mahallati, Hana, Castro, Leandro M., Tashima, Alexandre K., Ferro, Emer S., Fricker, Lloyd D.
Publicado 2015

Alterations of the Intracellular Peptidome in Response to the Proteasome Inhibitor Bortezomib

por Gelman, Julia S., Sironi, Juan, Berezniuk, Iryna, Dasgupta, Sayani, Castro, Leandro M., Gozzo, Fabio C., Ferro, Emer S., Fricker, Lloyd D.
Publicado 2013

Quantitative Peptidomics of Purkinje Cell Degeneration Mice

por Berezniuk, Iryna, Sironi, Juan J., Wardman, Jonathan, Pasek, Raymond C., Berbari, Nicolas F., Yoder, Bradley K., Fricker, Lloyd D.
Publicado 2013

Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain

por Garcia-Pardo, Javier, Tanco, Sebastian, Garcia-Guerrero, Maria C., Dasgupta, Sayani, Avilés, Francesc Xavier, Lorenzo, Julia, Fricker, Lloyd D.
Publicado 2020

Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains

por Garcia-Pardo, Javier, Tanco, Sebastian, Díaz, Lucía, Dasgupta, Sayani, Fernandez-Recio, Juan, Lorenzo, Julia, Aviles, Francesc X., Fricker, Lloyd D.
Publicado 2017

Analysis of the Yeast Peptidome and Comparison with the Human Peptidome

por Dasgupta, Sayani, Yang, Ciyu, Castro, Leandro M., Tashima, Alexandre K., Ferro, Emer S., Moir, Robyn D., Willis, Ian M., Fricker, Lloyd D.
Publicado 2016

Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment

por Aryal, Dipendra K., Rodriguiz, Ramona M., Nguyen, Ngoc Lien, Pease, Matthew W., Morgan, Daniel J., Pintar, John, Fricker, Lloyd D., Wetsel, William C.
Publicado 2022