Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945

por Beckmann, Nicolau, Giorgetti, Elisa, Neuhaus, Anna, Zurbruegg, Stefan, Accart, Nathalie, Smith, Paul, Perdoux, Julien, Perrot, Ludovic, Nash, Mark, Desrayaud, Sandrine, Wipfli, Peter, Frieauff, Wilfried, Shimshek, Derya R.
Publicado 2018

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

por Johns, Neil, Hatakeyama, Shinji, Stephens, Nathan A., Degen, Martin, Degen, Simone, Frieauff, Wilfried, Lambert, Christian, Ross, James A., Roubenoff, Ronenn, Glass, David J., Jacobi, Carsten, Fearon, Kenneth C. H.
Publicado 2014

Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model

por Beckmann, Nicolau, Neuhaus, Anna, Zurbruegg, Stefan, Volkmer, Pia, Patino, Claudia, Joller, Stefanie, Feuerbach, Dominik, Doelemeyer, Arno, Schweizer, Tatjana, Rudin, Stefan, Neumann, Ulf, Berth, Ramon, Frieauff, Wilfried, Gasparini, Fabrizio, Shimshek, Derya R.
Publicado 2023

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice

por Neumann, Ulf, Rueeger, Heinrich, Machauer, Rainer, Veenstra, Siem Jacob, Lueoend, Rainer M., Tintelnot-Blomley, Marina, Laue, Grit, Beltz, Karen, Vogg, Barbara, Schmid, Peter, Frieauff, Wilfried, Shimshek, Derya R., Staufenbiel, Matthias, Jacobson, Laura H.
Publicado 2015

Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys

por Theil, Diethilde, Smith, Paul, Huck, Catherine, Gilbart, Yoann, Kakarieka, Algirdas, Leppert, David, Rauld, Celine, Schmid, Cindy, Baumgartner, Reto, Stuber, Nathalie, Cordoba, Francisco, Dubost, Valerie, Darribat, Katy, Jivkov, Magali, Frieauff, Wilfried, Kneuer, Rainer, Stoeckli, Markus, Reinker, Stefan, Mansfield, Keith, Carballido, José M., Couttet, Philippe, Weckbecker, Gisbert
Publicado 2019

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease

por Neumann, Ulf, Ufer, Mike, Jacobson, Laura H, Rouzade‐Dominguez, Marie‐Laure, Huledal, Gunilla, Kolly, Carine, Lüönd, Rainer M, Machauer, Rainer, Veenstra, Siem J, Hurth, Konstanze, Rueeger, Heinrich, Tintelnot‐Blomley, Marina, Staufenbiel, Matthias, Shimshek, Derya R, Perrot, Ludovic, Frieauff, Wilfried, Dubost, Valerie, Schiller, Hilmar, Vogg, Barbara, Beltz, Karen, Avrameas, Alexandre, Kretz, Sandrine, Pezous, Nicole, Rondeau, Jean‐Michel, Beckmann, Nicolau, Hartmann, Andreas, Vormfelde, Stefan, David, Olivier J, Galli, Bruno, Ramos, Rita, Graf, Ana, Lopez Lopez, Cristina
Publicado 2018