ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data

por Friedman, Brad A, Maniatis, Tom
Publicado 2011

Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms

por Yap, Karen, Xiao, Yixin, Friedman, Brad A., Je, H. Shawn, Makeyev, Eugene V.
Publicado 2016

Clinico-morphological correlations in the categorization of holes between the ventricles

por Friedman, Brad A, Hlavacek, Anthony, Chessa, Karen, Shirali, Girish S, Corcrain, Eowyn, Spicer, Diane, Anderson, Robert H, Zyblewski, Sinai
Publicado 2010

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types

por Chen, Ying-Jiun J., Friedman, Brad A., Ha, Connie, Durinck, Steffen, Liu, Jinfeng, Rubenstein, John L., Seshagiri, Somasekar, Modrusan, Zora
Publicado 2017

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation

por Chang, Michael C., Srinivasan, Karpagam, Friedman, Brad A., Suto, Eric, Modrusan, Zora, Lee, Wyne P., Kaminker, Joshua S., Hansen, David V., Sheng, Morgan
Publicado 2017

Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq

por van Blitterswijk, Marka, Wang, Eric T., Friedman, Brad A., Keagle, Pamela J., Lowe, Patrick, Leclerc, Ashley Lyn, van den Berg, Leonard H., Housman, David E., Veldink, Jan H., Landers, John E.
Publicado 2013

Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

por Srinivasan, Karpagam, Friedman, Brad A., Etxeberria, Ainhoa, Huntley, Melanie A., van der Brug, Marcel P., Foreman, Oded, Paw, Jonathan S., Modrusan, Zora, Beach, Thomas G., Serrano, Geidy E., Hansen, David V.
Publicado 2020

TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice

por Wang, Yuanyuan, Wu, Tiffany, Tsai, Ming-Chi, Rezzonico, Mitchell G, Abdel-Haleem, Alyaa M, Xie, Luke, Gandham, Vineela D, Ngu, Hai, Stark, Kimberly, Glock, Caspar, Xu, Daqi, Foreman, Oded, Friedman, Brad A, Sheng, Morgan, Hanson, Jesse E
Publicado 2023

­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­

por Cuellar, Trinna L., Herzner, Anna-Maria, Zhang, Xiaotian, Goyal, Yogesh, Watanabe, Colin, Friedman, Brad A., Janakiraman, Vasantharajan, Durinck, Steffen, Stinson, Jeremy, Arnott, David, Cheung, Tommy K., Chaudhuri, Subhra, Modrusan, Zora, Doerr, Jonas Martin, Classon, Marie, Haley, Benjamin
Publicado 2017

Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses

por Srinivasan, Karpagam, Friedman, Brad A., Larson, Jessica L., Lauffer, Benjamin E., Goldstein, Leonard D., Appling, Laurie L., Borneo, Jovencio, Poon, Chungkee, Ho, Terence, Cai, Fang, Steiner, Pascal, van der Brug, Marcel P., Modrusan, Zora, Kaminker, Joshua S., Hansen, David V.
Publicado 2016

Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression

por Chen, Hsu-Hsin, Liu, Peter, Auger, Paul, Lee, Seung-Hye, Adolfsson, Oskar, Rey-Bellet, Lorianne, Lafrance-Vanasse, Julien, Friedman, Brad A., Pihlgren, Maria, Muhs, Andreas, Pfeifer, Andrea, Ernst, James, Ayalon, Gai, Wildsmith, Kristin R., Beach, Thomas G., van der Brug, Marcel P.
Publicado 2018

Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mou...

por Meilandt, William J., Ngu, Hai, Gogineni, Alvin, Lalehzadeh, Guita, Lee, Seung-Hye, Srinivasan, Karpagam, Imperio, Jose, Wu, Tiffany, Weber, Martin, Kruse, Agatha J., Stark, Kimberly L., Chan, Pamela, Kwong, Mandy, Modrusan, Zora, Friedman, Brad A., Elstrott, Justin, Foreman, Oded, Easton, Amy, Sheng, Morgan, Hansen, David V.
Publicado 2020

Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection

por Byrnes, Amy E., Dominguez, Sara L., Yen, Chun-Wan, Laufer, Benjamin I., Foreman, Oded, Reichelt, Mike, Lin, Han, Sagolla, Meredith, Hötzel, Kathy, Ngu, Hai, Soendergaard, Christoffer, Estevez, Alberto, Lin, Hsiu-Chao, Goyon, Alexandre, Bian, Juan, Lin, Jessica, Hinz, Flora I., Friedman, Brad A., Easton, Amy, Hoogenraad, Casper C.
Publicado 2023

Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models

por Dejanovic, Borislav, Wu, Tiffany, Tsai, Ming-Chi, Graykowski, David, Gandham, Vineela D., Rose, Christopher M., Bakalarski, Corey E., Ngu, Hai, Wang, Yuanyuan, Pandey, Shristi, Rezzonico, Mitchell G., Friedman, Brad A., Edmonds, Rose, De Mazière, Ann, Rakosi-Schmidt, Raphael, Singh, Tarjinder, Klumperman, Judith, Foreman, Oded, Chang, Michael C., Xie, Luke, Sheng, Morgan, Hanson, Jesse E.
Publicado 2022

TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models

por Dominguez, Sara L., Laufer, Benjamin I., Ghosh, Arundhati Sengupta, Li, Qingling, Ruggeri, Gaia, Emani, Maheswara Reddy, Phu, Lilian, Friedman, Brad A., Sandoval, Wendy, Rose, Christopher M., Ngu, Hai, Foreman, Oded, Reichelt, Mike, Juste, Yves, Lalehzadeh, Guita, Hansen, Dennis, Nymark, Helle, Mellal, Denia, Gylling, Helene, Kiełpiński, Łukasz J., Chih, Ben, Bingol, Baris, Hoogenraad, Casper C., Meilandt, William J., Easton, Amy
Publicado 2023