Fast-dissociating but highly specific antibodies are novel tools in biology, especially useful for multiplex super-resolution microscopy

por Miyoshi, Takushi, Friedman, Thomas B., Watanabe, Naoki
Publicado 2021

Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D

por Lagziel, Ayala, Overlack, Nora, Bernstein, Steven L., Morell, Robert J., Wolfrum, Uwe, Friedman, Thomas B.
Publicado 2009

The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness

por Jiang, Fangfang, Takagi, Yasuharu, Shams, Arik, Heissler, Sarah M., Friedman, Thomas B., Sellers, James R., Bird, Jonathan E.
Publicado 2021

Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

por Melli, Luca, Billington, Neil, Sun, Sara A, Bird, Jonathan E, Nagy, Attila, Friedman, Thomas B, Takagi, Yasuharu, Sellers, James R
Publicado 2018

Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse

por Yousaf, Rizwan, Gu, Chunfang, Ahmed, Zubair M., Khan, Shaheen N., Friedman, Thomas B., Riazuddin, Sheikh, Shears, Stephen B., Riazuddin, Saima
Publicado 2018

Phenotypic variability of CLDN14 mutations causing DFNB29 hearing loss in the Pakistani population

por Bashir, Zil-e-Huma, Latief, Noreen, Belyantseva, Inna A., Iqbal, Farheena, Riazuddin, S. Amer, Khan, Shaheen N., Friedman, Thomas B., Riazuddin, Sheikh, Riazuddin, Saima
Publicado 2012

Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

por Drummond, Meghan C., Barzik, Melanie, Bird, Jonathan E., Zhang, Duan-Sun, Lechene, Claude P., Corey, David P., Cunningham, Lisa L., Friedman, Thomas B.
Publicado 2015

Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells

por Indzhykulian, Artur A., Stepanyan, Ruben, Nelina, Anastasiia, Spinelli, Kateri J., Ahmed, Zubair M., Belyantseva, Inna A., Friedman, Thomas B., Barr-Gillespie, Peter G., Frolenkov, Gregory I.
Publicado 2013

Molecular and Clinical Studies of X-linked Deafness Among Pakistani Families

por Waryah, Ali M., Ahmed, Zubair M., Choo, Daniel I., Sisk, Robert A., Binder, Munir A., Shahzad, Mohsin, Khan, Shaheen N., Friedman, Thomas B., Riazuddin, Sheikh, Riazuddin, Saima
Publicado 2011

Variable expressivity of FGF3 mutations associated with deafness and LAMM syndrome

por Riazuddin, Saima, Ahmed, Zubair M, Hegde, Rashmi S, Khan, Shaheen N, Nasir, Idrees, Shaukat, Uzma, Riazuddin, Sheikh, Butman, John A, Griffith, Andrew J, Friedman, Thomas B, Choi, Byung Yoon
Publicado 2011

The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing

por Fang, Qing, Indzhykulian, Artur A, Mustapha, Mirna, Riordan, Gavin P, Dolan, David F, Friedman, Thomas B, Belyantseva, Inna A, Frolenkov, Gregory I, Camper, Sally A, Bird, Jonathan E
Publicado 2015

Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP

por Babahosseini, Hesam, Belyantseva, Inna A., Yousaf, Rizwan, Tona, Risa, Hadi, Shadan, Inagaki, Sayaka, Wilson, Elizabeth, Kitajiri, Shin-ichiro, Frolenkov, Gregory I., Friedman, Thomas B., Cartagena-Rivera, Alexander X.
Publicado 2022

Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration

por Ahmed, Zubair M., Kjellstrom, Sten, Haywood-Watson, Ricky J. L., Bush, Ronald A., Hampton, Lori L., Battey, James F., Riazuddin, Saima, Frolenkov, Gregory, Sieving, Paul A., Friedman, Thomas B.
Publicado 2008

Semi-automated single-molecule microscopy screening of fast-dissociating specific antibodies directly from hybridoma cultures

por Miyoshi, Takushi, Zhang, Qianli, Miyake, Takafumi, Watanabe, Shin, Ohnishi, Hiroe, Chen, Jiji, Vishwasrao, Harshad D., Chakraborty, Oisorjo, Belyantseva, Inna A., Perrin, Benjamin J., Shroff, Hari, Friedman, Thomas B., Omori, Koichi, Watanabe, Naoki
Publicado 2021

Proposed therapy, developed in a Pcdh15-deficient mouse, for progressive loss of vision in human Usher syndrome

por Sethna, Saumil, Zein, Wadih M, Riaz, Sehar, Giese, Arnaud PJ, Schultz, Julie M, Duncan, Todd, Hufnagel, Robert B, Brewer, Carmen C, Griffith, Andrew J, Redmond, T Michael, Riazuddin, Saima, Friedman, Thomas B, Ahmed, Zubair M
Publicado 2021

Vestibular phenotype‐genotype correlation in a cohort of 90 patients with Usher syndrome

por Wafa, Talah T., Faridi, Rabia, King, Kelly A., Zalewski, Christopher, Yousaf, Rizwan, Schultz, Julie M., Morell, Robert J., Muskett, Julie, Turriff, Amy, Tsilou, Ekaterini, Griffith, Andrew J., Friedman, Thomas B., Zein, Wadih M., Brewer, Carmen C.
Publicado 2020

Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness

por Tona, Risa, Lopez, Ivan A., Fenollar-Ferrer, Cristina, Faridi, Rabia, Anselmi, Claudio, Khan, Asma A., Shahzad, Mohsin, Morell, Robert J., Gu, Shoujun, Hoa, Michael, Dong, Lijin, Ishiyama, Akira, Belyantseva, Inna A., Riazuddin, Sheikh, Friedman, Thomas B.
Publicado 2020

Genomic analysis of childhood hearing loss in the Yoruba population of Nigeria

por Adeyemo, Adebolajo, Faridi, Rabia, Chattaraj, Parna, Yousaf, Rizwan, Tona, Risa, Okorie, Samuel, Bharadwaj, Thashi, Nouel-Saied, Liz M., Acharya, Anushree, Schrauwen, Isabelle, Morell, Robert J., Leal, Suzanne M., Friedman, Thomas B., Griffith, Andrew J., Roux, Isabelle
Publicado 2021

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B

por Lau, Samantha C., Grati, Mhamed, Isgrig, Kevin, Sinan, Moaz, Calabro, Kaitlyn R., Zhu, Jianliang, Ishibashi, Yasuko, Ozgur, Zeynep, Wafa, Talah, Belyantseva, Inna A., Fitzgerald, Tracy, Friedman, Thomas B., Boye, Sanford L., Boye, Shannon E., Chien, Wade W.
Publicado 2023

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

por Morozko, Eva L., Nishio, Ayako, Ingham, Neil J., Chandra, Rashmi, Fitzgerald, Tracy, Martelletti, Elisa, Borck, Guntram, Wilson, Elizabeth, Riordan, Gavin P., Wangemann, Philine, Forge, Andrew, Steel, Karen P., Liddle, Rodger A., Friedman, Thomas B., Belyantseva, Inna A.
Publicado 2015