The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization

por Friel, Claire T, Howard, Jonathon
Publicado 2011

Coupling of kinesin ATP turnover to translocation and microtubule regulation: one engine, many machines

por Friel, Claire T., Howard, Jonathon
Publicado 2012

A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition

por Belsham, Hannah R., Friel, Claire T.
Publicado 2017

Parts list for a microtubule depolymerising kinesin

por Friel, Claire T., Welburn, Julie P.
Publicado 2018

Identification of key residues that regulate the interaction of kinesins with microtubule ends

por Belsham, Hannah R., Friel, Claire T.
Publicado 2019

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target

por Sanhaji, Mourad, Friel, Claire T., Wordeman, Linda, Louwen, Frank, Yuan, Juping
Publicado 2011

Use of Stopped-Flow Fluorescence and Labeled Nucleotides to Analyze the ATP Turnover Cycle of Kinesins

por Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Friel, Claire T.
Publicado 2014

The Mechanism of Folding of Im7 Reveals Competition between Functional and Kinetic Evolutionary Constraints

por Friel, Claire T., Smith, D. Alastair, Vendruscolo, Michele, Gsponer, Joerg, Radford, Sheena E.
Publicado 2009

The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition

por Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Wickstead, Bill, Gell, Christopher, Friel, Claire T.
Publicado 2016

Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis

por Sanhaji, Mourad, Ritter, Andreas, Belsham, Hannah R., Friel, Claire T., Roth, Susanne, Louwen, Frank, Yuan, Juping
Publicado 2014

A synthetic ancestral kinesin-13 depolymerizes microtubules faster than any natural depolymerizing kinesin

por Belsham, Hannah R., Alghamdi, Hanan M., Dave, Nikita, Rathbone, Alexandra J., Wickstead, Bill, Friel, Claire T.
Publicado 2022

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

por Qu, Yue, Hahn, Ines, Lees, Meredith, Parkin, Jill, Voelzmann, André, Dorey, Karel, Rathbone, Alex, Friel, Claire T, Allan, Victoria J, Okenve-Ramos, Pilar, Sanchez-Soriano, Natalia, Prokop, Andreas
Publicado 2019