Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization

por Horn, Jacqueline, Friess, Wolfgang
Publicado 2018

Energy Transfer in Vials Nested in a Rack System During Lyophilization

por Daller, Sarah, Friess, Wolfgang, Schroeder, Rudolf
Publicado 2020

Coupling Multi-Angle Light Scattering to Reverse-Phase Ultra-High-Pressure Chromatography (RP-UPLC-MALS) for the characterization monoclonal antibodies

por Gentiluomo, Lorenzo, Schneider, Vanessa, Roessner, Dierk, Frieß, Wolfgang
Publicado 2019

Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

por Higel, Fabian, Demelbauer, Uwe, Seidl, Andreas, Friess, Wolfgang, Sörgel, Fritz
Publicado 2013

Small scale affinity purification and high sensitivity reversed phase nanoLC-MS N-glycan characterization of mAbs and fusion proteins

por Higel, Fabian, Seidl, Andreas, Demelbauer, Uwe, Sörgel, Fritz, Frieß, Wolfgang
Publicado 2014

Be Aggressive! Amorphous Excipients Enabling Single-Step Freeze-Drying of Monoclonal Antibody Formulations

por Haeuser, Christina, Goldbach, Pierre, Huwyler, Joerg, Friess, Wolfgang, Allmendinger, Andrea
Publicado 2019

A model-based optimization strategy to achieve fast and robust freeze-drying cycles

por Vanbillemont, Brecht, Greiner, Anna-Lena, Ehrl, Vanessa, Menzen, Tim, Friess, Wolfgang, Hawe, Andrea
Publicado 2023

Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients

por Bluemel, Oliver, Buecheler, Jakob W., Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline, Friess, Wolfgang
Publicado 2021

The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – part 2: Aggregate formation and oxidation

por Bluemel, Oliver, Buecheler, Jakob W., Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline, Friess, Wolfgang
Publicado 2021

The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – Part 1: Higher molecular weight species and subvisible particle formation

por Bluemel, Oliver, Anuschek, Moritz, Buecheler, Jakob W., Hoelzl, Georg, Bechtold-Peters, Karoline, Friess, Wolfgang
Publicado 2021

SV-AUC as a stability-indicating method for the characterization of mRNA-LNPs

por Thaller, Anian, Schmauder, Lukas, Frieß, Wolfgang, Winter, Gerhard, Menzen, Tim, Hawe, Andrea, Richter, Klaus
Publicado 2023

N-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceu...

por Higel, Fabian, Seidl, Andreas, Demelbauer, Uwe, Viertlboeck-Schudy, Margot, Koppenburg, Vera, Kronthaler, Ulrich, Sörgel, Fritz, Frieß, Wolfgang
Publicado 2015

Zn(2+)-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils

por Yordanova, Yordanka, Vanderlinden, Willem, Stoll, Raphael, Rüdiger, Daniel, Tosstorff, Andreas, Zaremba, Wolfgang, Winter, Gerhard, Zahler, Stefan, Friess, Wolfgang
Publicado 2018

Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin

por Kulakova, Alina, Indrakumar, Sowmya, Sønderby, Pernille, Gentiluomo, Lorenzo, Streicher, Werner, Roessner, Dierk, Frieß, Wolfgang, Peters, Günther H.J., Harris, Pernille
Publicado 2019

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

por Gerckens, Michael, Schorpp, Kenji, Pelizza, Francesco, Wögrath, Melanie, Reichau, Kora, Ma, Huilong, Dworsky, Armando-Marco, Sengupta, Arunima, Stoleriu, Mircea Gabriel, Heinzelmann, Katharina, Merl-Pham, Juliane, Irmler, Martin, Alsafadi, Hani N., Trenkenschuh, Eduard, Sarnova, Lenka, Jirouskova, Marketa, Frieß, Wolfgang, Hauck, Stefanie M., Beckers, Johannes, Kneidinger, Nikolaus, Behr, Jürgen, Hilgendorff, Anne, Hadian, Kamyar, Lindner, Michael, Königshoff, Melanie, Eickelberg, Oliver, Gregor, Martin, Plettenburg, Oliver, Yildirim, Ali Önder, Burgstaller, Gerald
Publicado 2021