Nuclear receptors: from molecular mechanisms to therapeutics

por Frigo, Daniel E., Bondesson, Maria, Williams, Cecilia
Publicado 2021

Editorial: Metabolic regulation under oxidative stress in cancer

por Subramani, Elavarasan, Dominic, Abishai, Bhattacharya, Pratip K., Frigo, Daniel E., Bederman, Ilya, Vaziri-Gohar, Ali
Publicado 2023

DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms.

por Frigo, Daniel E, Burow, Matthew E, Mitchell, Kamron A, Chiang, Tung-Chin, McLachlan, John A
Publicado 2002

The Organochlorine o,p’-DDT Plays a Role in Coactivator-Mediated MAPK Crosstalk in MCF-7 Breast Cancer Cells

por Bratton, Melyssa R., Frigo, Daniel E., Segar, H. Chris, Nephew, Kenneth P., McLachlan, John A., Wiese, Thomas E., Burow, Matthew E.
Publicado 2012

A simple quantitative PCR assay to determine TRAMP transgene zygosity

por Chen, Ruidong, Liang, Xin, Murray, Mollianne M., Karasik, Ellen, Han, Jenny J., Zhu, Ming, Foster, Barbara A., Frigo, Daniel E., Wang, Guocan
Publicado 2020

SAT634 The Androgen Receptor Does Not Directly Regulate The Transcription Of DNA Damage Response Genes

por Hasterok, Sylwia, Scott, Thomas G, Roller, Devin G, Spencer, Adam, Dutta, Arun B, Sathyan, Kizhakke Mattada, Frigo, Daniel E, Guertin, Michael J, Gioeli, Daniel
Publicado 2023

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

por Dahl, Haley C., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Sandhu, Amrit, Kanumuri, Preethi, Nawas, Afshan F., Xing, Chao, Lin, Chenchu, Frigo, Daniel E., Delk, Nikki A.
Publicado 2020

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

por Shafi, Ayesha A., Putluri, Vasanta, Arnold, James M., Tsouko, Efrosini, Maity, Suman, Roberts, Justin M., Coarfa, Cristian, Frigo, Daniel E., Putluri, Nagireddy, Sreekumar, Arun, Weigel, Nancy L.
Publicado 2015

Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer

por Pulliam, Thomas L., Awad, Dominik, Han, Jenny J., Murray, Mollianne M., Ackroyd, Jeffrey J., Goli, Pavithr, Oakhill, Jonathan S., Scott, John W., Ittmann, Michael M., Frigo, Daniel E.
Publicado 2022

Assessing Therapeutic Efficacy in Real-time by Hyperpolarized Magnetic Resonance Metabolic Imaging

por Dutta, Prasanta, Salzillo, Travis C., Pudakalakatti, Shivanand, Gammon, Seth T., Kaipparettu, Benny A., McAllister, Florencia, Wagner, Shawn, Frigo, Daniel E., Logothetis, Christopher J., Zacharias, Niki M., Bhattacharya, Pratip K.
Publicado 2019

Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy

por Gaur, Sanchaika, Wen, Yunfei, Song, Jian H., Parikh, Nila U., Mangala, Lingegowda S., Blessing, Alicia M., Ivan, Cristina, Wu, Sherry Y., Varkaris, Andreas, Shi, Yan, Lopez-Berestein, Gabriel, Frigo, Daniel E., Sood, Anil K., Gallick, Gary E.
Publicado 2015

Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling

por Lin, Chenchu, Blessing, Alicia M., Pulliam, Thomas L., Shi, Yan, Wilkenfeld, Sandi R., Han, Jenny J., Murray, Mollianne M., Pham, Alexander H., Duong, Kevin, Brun, Sonja N., Shaw, Reuben J., Ittmann, Michael M., Frigo, Daniel E.
Publicado 2021

Androgens Regulate Prostate Cancer Cell Growth via an AMPK-PGC-1α-Mediated Metabolic Switch

por Tennakoon, Jayantha B., Shi, Yan, Han, Jenny J., Tsouko, Efrosini, White, Mark A., Burns, Alan R., Zhang, Aijun, Xia, Xuefeng, Ilkayeva, Olga R., Xin, Li, Ittmann, Michael M., Rick, Ferenc G., Schally, Andrew V., Frigo, Daniel E.
Publicado 2013

SGC-CAMKK2-1: A Chemical Probe for CAMKK2

por Wells, Carrow, Liang, Yi, Pulliam, Thomas L., Lin, Chenchu, Awad, Dominik, Eduful, Benjamin, O’Byrne, Sean, Hossain, Mohammad Anwar, Catta-Preta, Carolina Moura Costa, Ramos, Priscila Zonzini, Gileadi, Opher, Gileadi, Carina, Couñago, Rafael M., Stork, Brittany, Langendorf, Christopher G., Nay, Kevin, Oakhill, Jonathan S., Mukherjee, Debarati, Racioppi, Luigi, Means, Anthony R., York, Brian, McDonnell, Donald P., Scott, John W., Frigo, Daniel E., Drewry, David H.
Publicado 2023

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

por Eduful, Benjamin J., O’Byrne, Sean N., Temme, Louisa, Asquith, Christopher R. M., Liang, Yi, Picado, Alfredo, Pilotte, Joseph R., Hossain, Mohammad Anwar, Wells, Carrow I., Zuercher, William J., Catta-Preta, Carolina M. C., Zonzini Ramos, Priscila, Santiago, André de S., Couñago, Rafael M., Langendorf, Christopher G., Nay, Kévin, Oakhill, Jonathan S., Pulliam, Thomas L., Lin, Chenchu, Awad, Dominik, Willson, Timothy M., Frigo, Daniel E., Scott, John W., Drewry, David H.
Publicado 2021

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

por Kaushik, Akash K., Shojaie, Ali, Panzitt, Katrin, Sonavane, Rajni, Venghatakrishnan, Harene, Manikkam, Mohan, Zaslavsky, Alexander, Putluri, Vasanta, Vasu, Vihas T., Zhang, Yiqing, Khan, Ayesha S., Lloyd, Stacy, Szafran, Adam T., Dasgupta, Subhamoy, Bader, David A., Stossi, Fabio, Li, Hangwen, Samanta, Susmita, Cao, Xuhong, Tsouko, Efrosini, Huang, Shixia, Frigo, Daniel E., Chan, Lawrence, Edwards, Dean P., Kaipparettu, Benny A., Mitsiades, Nicholas, Weigel, Nancy L., Mancini, Michael, McGuire, Sean E., Mehra, Rohit, Ittmann, Michael M., Chinnaiyan, Arul M., Putluri, Nagireddy, Palapattu, Ganesh S., Michailidis, George, Sreekumar, Arun
Publicado 2016

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

por Xu, Weiwei, Qadir, M.M. Fahd, Nasteska, Daniela, de Sa, Paula Mota, Gorvin, Caroline M., Blandino-Rosano, Manuel, Evans, Charles R., Ho, Thuong, Potapenko, Evgeniy, Veluthakal, Rajakrishnan, Ashford, Fiona B., Bitsi, Stavroula, Fan, Jia, Bhondeley, Manika, Song, Kejing, Sure, Venkata N., Sakamuri, Siva S.V.P., Schiffer, Lina, Beatty, Wandy, Wyatt, Rachael, Frigo, Daniel E., Liu, Xiaowen, Katakam, Prasad V., Arlt, Wiebke, Buck, Jochen, Levin, Lonny R., Hu, Tony, Kolls, Jay, Burant, Charles F., Tomas, Alejandra, Merrins, Matthew J., Thurmond, Debbie C., Bernal-Mizrachi, Ernesto, Hodson, David J., Mauvais-Jarvis, Franck
Publicado 2023