Therapeutic Targeting of Hyaluronan in the Tumor Stroma

por Kultti, Anne, Li, Xiaoming, Jiang, Ping, Thompson, Curtis B., Frost, Gregory I., Shepard, H. Michael
Publicado 2012

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions

por Marella, Mathieu, Jadin, Laurence, Keller, Gilbert A, Sugarman, Barry J, Frost, Gregory I, Shepard, H Michael
Publicado 2018

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours

por Infante, Jeffrey R, Korn, Ronald L, Rosen, Lee S, LoRusso, Patricia, Dychter, Samuel S, Zhu, Joy, Maneval, Daniel C, Jiang, Ping, Shepard, H Michael, Frost, Gregory, Von Hoff, Daniel D, Borad, Mitesh J, Ramanathan, Ramesh K
Publicado 2018

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours

por Infante, Jeffrey R, Korn, Ronald L, Rosen, Lee S, LoRusso, Patricia, Dychter, Samuel S, Zhu, Joy, Maneval, Daniel C, Jiang, Ping, Shepard, H Michael, Frost, Gregory, Von Hoff, Daniel D, Borad, Mitesh J, Ramanathan, Ramesh K
Publicado 2018

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

por Rosengren, Sanna, Dychter, Samuel S., Printz, Marie A., Huang, Lei, Schiff, Richard I., Schwarz, Hans-Peter, McVey, John K., Drake, Fred H., Maneval, Dan C., Kennard, Don A., Frost, Gregory I., Sugarman, Barry J., Muchmore, Douglas B.
Publicado 2015

Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment

por Kultti, Anne, Zhao, Chunmei, Singha, Netai C., Zimmerman, Susan, Osgood, Ryan J., Symons, Rebecca, Jiang, Ping, Li, Xiaoming, Thompson, Curtis B., Infante, Jeffrey R., Jacobetz, Michael A., Tuveson, David A., Frost, Gregory I., Shepard, H. Michael, Huang, Zhongdong
Publicado 2014

PH20 is not expressed in murine CNS and oligodendrocyte precursor cells

por Marella, Mathieu, Ouyang, Joe, Zombeck, Jonathan, Zhao, Chunmei, Huang, Lei, Connor, Robert J., Phan, Kim B., Jorge, Michael C., Printz, Marie A., Paladini, Rudolph D., Gelb, Arnold B., Huang, Zhongdong, Frost, Gregory I., Sugarman, Barry J., Steinman, Lawrence, Wei, Ge, Shepard, H. Michael, Maneval, Daniel C., Lapinskas, Paula J.
Publicado 2017

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

por Jacobetz, Michael A, Chan, Derek S, Neesse, Albrecht, Bapiro, Tashinga E, Cook, Natalie, Frese, Kristopher K, Feig, Christine, Nakagawa, Tomoaki, Caldwell, Meredith E, Zecchini, Heather I, Lolkema, Martijn P, Jiang, Ping, Kultti, Anne, Thompson, Curtis B, Maneval, Daniel C, Jodrell, Duncan I, Frost, Gregory I, Shepard, H M, Skepper, Jeremy N, Tuveson, David A
Publicado 2013