Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects

por Frozza, Rudimar L., Lourenco, Mychael V., De Felice, Fernanda G.
Publicado 2018

The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pa...

por Bernardi, Andressa, Frozza, Rudimar L, Hoppe, Juliana B, Salbego, Christianne, Pohlmann, Adriana R, Battastini, Ana Maria O, Guterres, Sílvia S
Publicado 2013

Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Aβ1-42 in Alzheimer’s disease models

por Bernardi, Andressa, Frozza, Rudimar L, Meneghetti, André, Hoppe, Juliana B, Battastini, Ana Maria O, Pohlmann, Adriana R, Guterres, Sílvia S, Salbego, Christianne G
Publicado 2012

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation

por Clarke, Julia R, Lyra e Silva, Natalia M, Figueiredo, Claudia P, Frozza, Rudimar L, Ledo, Jose H, Beckman, Danielle, Katashima, Carlos K, Razolli, Daniela, Carvalho, Bruno M, Frazão, Renata, Silveira, Marina A, Ribeiro, Felipe C, Bomfim, Theresa R, Neves, Fernanda S, Klein, William L, Medeiros, Rodrigo, LaFerla, Frank M, Carvalheira, Jose B, Saad, Mario J, Munoz, Douglas P, Velloso, Licio A, Ferreira, Sergio T, De Felice, Fernanda G
Publicado 2015

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

por Lourenco, Mychael V., Frozza, Rudimar L., de Freitas, Guilherme B., Zhang, Hong, Kincheski, Grasielle C., Ribeiro, Felipe C., Gonçalves, Rafaella A., Clarke, Julia R., Beckman, Danielle, Staniszewski, Agnieszka, Berman, Hanna, Guerra, Lorena A., Forny-Germano, Letícia, Meier, Shelby, Wilcock, Donna M., de Souza, Jorge M., Alves-Leon, Soniza, Prado, Vania F., Prado, Marco A. M., Abisambra, Jose F., Tovar-Moll, Fernanda, Mattos, Paulo, Arancio, Ottavio, Ferreira, Sergio T., De Felice, Fernanda G.
Publicado 2019