Engineering of Three-Finger Fold Toxins Creates Ligands with Original Pharmacological Profiles for Muscarinic and Adrenergic Receptors

por Fruchart-Gaillard, Carole, Mourier, Gilles, Blanchet, Guillaume, Vera, Laura, Gilles, Nicolas, Ménez, Renée, Marcon, Elodie, Stura, Enrico A., Servent, Denis
Publicado 2012

Copper mediated amyloid-β binding to Transthyretin

por Ciccone, Lidia, Fruchart-Gaillard, Carole, Mourier, Gilles, Savko, Martin, Nencetti, Susanna, Orlandini, Elisabetta, Servent, Denis, Stura, Enrico A., Shepard, William
Publicado 2018

New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer’s Disease

por Ciccone, Lidia, Camodeca, Caterina, Tonali, Nicolò, Barlettani, Lucia, Rossello, Armando, Fruchart Gaillard, Carole, Kaffy, Julia, Petrarolo, Giovanni, La Motta, Concettina, Nencetti, Susanna, Orlandini, Elisabetta
Publicado 2023

Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress

por Ciccone, Lidia, Petrarolo, Giovanni, Barsuglia, Francesca, Fruchart-Gaillard, Carole, Cassar Lajeunesse, Evelyne, Adewumi, Adeniyi T., Soliman, Mahmoud E. S., La Motta, Concettina, Orlandini, Elisabetta, Nencetti, Susanna
Publicado 2022

SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2

por Essalmani, Rachid, Andréo, Ursula, Evagelidis, Alexandra, Le Dévéhat, Maïlys, Pereira Ramos, Oscar Henrique, Fruchart Gaillard, Carole, Susan-Resiga, Delia, Cohen, Éric A., Seidah, Nabil G.
Publicado 2023

The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases

por Abd-Ella, Aly, Stankiewicz, Maria, Mikulska, Karolina, Nowak, Wieslaw, Pennetier, Cédric, Goulu, Mathilde, Fruchart-Gaillard, Carole, Licznar, Patricia, Apaire-Marchais, Véronique, List, Olivier, Corbel, Vincent, Servent, Denis, Lapied, Bruno
Publicado 2015

High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli

por Nozach, Hervé, Fruchart-Gaillard, Carole, Fenaille, François, Beau, Fabrice, Ramos, Oscar Henrique Pereira, Douzi, Badreddine, Saez, Natalie J, Moutiez, Mireille, Servent, Denis, Gondry, Muriel, Thaï, Robert, Cuniasse, Philippe, Vincentelli, Renaud, Dive, Vincent
Publicado 2013

Orthosteric Binding of ρ-Da1a, a Natural Peptide of Snake Venom Interacting Selectively with the α(1A)-Adrenoceptor

por Maïga, Arhamatoulaye, Merlin, Jon, Marcon, Elodie, Rouget, Céline, Larregola, Maud, Gilquin, Bernard, Fruchart-Gaillard, Carole, Lajeunesse, Evelyne, Marchetti, Charles, Lorphelin, Alain, Bellanger, Laurent, Summers, Roger J., Hutchinson, Dana S., Evans, Bronwyn A., Servent, Denis, Gilles, Nicolas
Publicado 2013

Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels

por Fruchart Gaillard, Carole, Ouadda, Ali Ben Djoudi, Ciccone, Lidia, Girard, Emmanuelle, Mikaeeli, Sepideh, Evagelidis, Alexandra, Le Dévéhat, Maïlys, Susan-Resiga, Delia, Lajeunesse, Evelyne Cassar, Nozach, Hervé, Ramos, Oscar Henrique Pereira, Thureau, Aurélien, Legrand, Pierre, Prat, Annik, Dive, Vincent, Seidah, Nabil G.
Publicado 2022

Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases

por Vadon-Le Goff, Sandrine, Tessier, Agnès, Napoli, Manon, Dieryckx, Cindy, Bauer, Julien, Dussoyer, Mélissa, Lagoutte, Priscillia, Peyronnel, Célian, Essayan, Lucie, Kleiser, Svenja, Tueni, Nicole, Bettler, Emmanuel, Mariano, Natacha, Errazuriz-Cerda, Elisabeth, Fruchart Gaillard, Carole, Ruggiero, Florence, Becker-Pauly, Christoph, Allain, Jean-Marc, Bruckner-Tuderman, Leena, Nyström, Alexander, Moali, Catherine
Publicado 2023