Beyond CD19: Opportunities for Future Development of Targeted Immunotherapy in Pediatric Relapsed-Refractory Acute Leukemia

por Shalabi, Haneen, Angiolillo, Anne, Fry, Terry J.
Publicado 2015

Murine Models of Acute Leukemia: Important Tools in Current Pediatric Leukemia Research

por Jacoby, Elad, Chien, Christopher D., Fry, Terry J.
Publicado 2014

Myeloablative hematopoietic stem cell transplantation improves survival but is not curative in a pre-clinical model of myelodysplastic syndrome

por Chung, Yang Jo, Fry, Terry J., Aplan, Peter D.
Publicado 2017

Bioinformatic Description of Immunotherapy Targets for Pediatric T-Cell Leukemia and the Impact of Normal Gene Sets Used for Comparison

por Orentas, Rimas J., Nordlund, Jessica, He, Jianbin, Sindiri, Sivasish, Mackall, Crystal, Fry, Terry J., Khan, Javed
Publicado 2014

Val-BoroPro Accelerates T Cell Priming via Modulation of Dendritic Cell Trafficking Resulting in Complete Regression of Established Murine Tumors

por Walsh, Meghaan P., Duncan, Brynn, Larabee, Shannon, Krauss, Aviva, Davis, Jessica P. E., Cui, Yongzhi, Kim, Su Young, Guimond, Martin, Bachovchin, William, Fry, Terry J.
Publicado 2013

Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells

por Stroncek, David F., Lee, Daniel W., Ren, Jiaqiang, Sabatino, Marianna, Highfill, Steven, Khuu, Hanh, Shah, Nirali N., Kaplan, Rosandra N., Fry, Terry J., Mackall, Crystal L.
Publicado 2017

Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22

por Qin, Haiying, Ramakrishna, Sneha, Nguyen, Sang, Fountaine, Thomas J., Ponduri, Anusha, Stetler-Stevenson, Maryalice, Yuan, Constance M., Haso, Waleed, Shern, Jack F., Shah, Nirali N., Fry, Terry J.
Publicado 2018

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3-mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leuk...

por Niswander, Lisa M., Graff, Zachary T., Chien, Christopher D., Chukinas, John A., Meadows, Christina A., Leach, Lillie C., Loftus, Joseph P., Kohler, M. Eric, Tasian, Sarah K., Fry, Terry J.
Publicado 2022

EPEN-26. Chemokine receptor blockade reverses CCL2 mediated immunosuppression and restores CAR-T cell function in posterior fossa ependymoma

por Cole, Allison P, Donson, Andrew M, Pierce, Angela M, Grimaldo, Enrique, Calhoun, Jacob D, Griesinger, Andrea M, Sublett, Caroline, Kaplan, Rosandra N, Fry, Terry J, Foreman, Nicholas K, Nellan, Anandani
Publicado 2022

Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design

por Qin, Haiying, Yang, Lila, Chukinas, John A, Shah, Nirali N, Tarun, Samiksha, Pouzolles, Marie, Chien, Christopher D, Niswander, Lisa M, Welch, Anthony R, Taylor, Naomi A, Tasian, Sarah K, Fry, Terry J
Publicado 2021

Combining Immunocytokine and Ex Vivo Activated NK Cells as a Platform for Enhancing Graft-Versus-Tumor Effects Against GD2(+) Murine Neuroblastoma

por Bates, Paul D., Rakhmilevich, Alexander L., Cho, Monica M., Bouchlaka, Myriam N., Rao, Seema L., Hales, Joanna M., Orentas, Rimas J., Fry, Terry J., Gilles, Stephen D., Sondel, Paul M., Capitini, Christian M.
Publicado 2021

The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes

por Faruqi, Aiman J., Ligon, John A., Borgman, Paul, Steinberg, Seth M., Foley, Toni, Little, Lauren, Mackall, Crystal L., Lee, Daniel W., Fry, Terry J., Shalabi, Haneen, Brudno, Jennifer, Yates, Bonnie, Mikkilineni, Lekha, Kochenderfer, James, Shah, Nirali N.
Publicado 2022

4-1BB Costimulation Ameliorates T Cell Exhaustion Induced by Tonic Signaling of Chimeric Antigen Receptors

por Long, Adrienne H., Haso, Waleed M., Shern, Jack F., Wanhainen, Kelsey M., Murgai, Meera, Ingaramo, Maria, Smith, Jillian P., Walker, Alec J., Kohler, M. Eric, Venkateshwara, Vikas R., Kaplan, Rosandra N., Patterson, George H., Fry, Terry J., Orentas, Rimas J., Mackall, Crystal L.
Publicado 2015

Efficacy of second CAR-T (CART2) infusion limited by poor CART expansion and antigen modulation

por Holland, Elizabeth M, Molina, John C, Dede, Kniya, Moyer, Daniel, Zhou, Ting, Yuan, Constance M, Wang, Hao-Wei, Stetler-Stevenson, Maryalice, Mackall, Crystal, Fry, Terry J, Panch, Sandhya, Highfill, Steven, Stroncek, David, Little, Lauren, Lee, Daniel W, Shalabi, Haneen, Yates, Bonnie, Shah, Nirali
Publicado 2022

Murine allogeneic CAR T cells integrated before or early after posttransplant cyclophosphamide exert antitumor effects

por Patterson, Michael T., Khan, Shanzay M., Nunes, Natalia S., Fletcher, Rochelle E., Bian, Jing, Hadjis, Ashley D., Eckhaus, Michael A., Mendu, Suresh K., de Paula Pohl, Alessandra, Venzon, David J., Choo-Wosoba, Hyoyoung, Ishii, Kazusa, Qin, Haiying, Fry, Terry J., Cam, Maggie, Kanakry, Christopher G.
Publicado 2023

Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice

por Hu, Xiaomeng, Manner, Karl, DeJesus, Rowena, White, Kathy, Gattis, Corie, Ngo, Priscilla, Bandoro, Christopher, Tham, Eleonore, Chu, Elaine Y., Young, Chi, Wells, Frank, Basco, Ronald, Friera, Annabelle, Kangeyan, Divy, Beauchesne, Pascal, Dowdle, William E., Deuse, Tobias, Fry, Terry J., Foster, Aaron E., Schrepfer, Sonja
Publicado 2023

CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity

por Jess, Jennifer, Yates, Bonnie, Dulau-Florea, Alina, Parker, Kevin, Inglefield, Jon, Lichtenstein, Dan, Schischlik, Fiorella, Ongkeko, Martin, Wang, Yanyu, Shahani, Shilpa, Cullinane, Ann, Smith, Hannah, Kane, Eli, Little, Lauren, Chen, Dong, Fry, Terry J, Shalabi, Haneen, Wang, Hao-Wei, Satpathy, Ansuman, Lozier, Jay, Shah, Nirali N
Publicado 2023

CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity

por Jacoby, Elad, Nguyen, Sang M., Fountaine, Thomas J., Welp, Kathryn, Gryder, Berkley, Qin, Haiying, Yang, Yinmeng, Chien, Christopher D., Seif, Alix E., Lei, Haiyan, Song, Young K., Khan, Javed, Lee, Daniel W., Mackall, Crystal L., Gardner, Rebecca A., Jensen, Michael C., Shern, Jack F., Fry, Terry J.
Publicado 2016

Diagnostic approach to the evaluation of myeloid malignancies following CAR T-cell therapy in B-cell acute lymphoblastic leukemia

por Mo, George, Wang, Hao-Wei, Talleur, Aimee C, Shahani, Shilpa A, Yates, Bonnie, Shalabi, Haneen, Douvas, Michael G, Calvo, Katherine R, Shern, Jack F, Chaganti, Sridhar, Patrick, Katharine, Song, Young, Fry, Terry J, Wu, Xiaolin, Triplett, Brandon M, Khan, Javed, Gardner, Rebecca A, Shah, Nirali N
Publicado 2020

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

por Sportès, Claude, Hakim, Frances T., Memon, Sarfraz A., Zhang, Hua, Chua, Kevin S., Brown, Margaret R., Fleisher, Thomas A., Krumlauf, Michael C., Babb, Rebecca R., Chow, Catherine K., Fry, Terry J., Engels, Julie, Buffet, Renaud, Morre, Michel, Amato, Robert J., Venzon, David J., Korngold, Robert, Pecora, Andrew, Gress, Ronald E., Mackall, Crystal L.
Publicado 2008