SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells

por Wang, Yan, Wang, Jing-Miao, Xiao, Yuan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Zhang, Lan, Gan, Yu-Wen, Liang, Xing-Miao, Li, David Wan-Cheng
Publicado 2023

Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration

por Zou, Ming, Ke, Qin, Nie, Qian, Qi, Ruili, Zhu, Xingfei, Liu, Wei, Hu, Xuebin, Sun, Qian, Fu, Jia-Ling, Tang, Xiangcheng, Liu, Yizhi, Li, David Wan-Cheng, Gong, Lili
Publicado 2022

The transcription factor CREB acts as an important regulator mediating oxidative stress-induced apoptosis by suppressing αB-crystallin expression

por Wang, Ling, Nie, Qian, Gao, Meng, Yang, Lan, Xiang, Jia-Wen, Xiao, Yuan, Liu, Fang-Yuan, Gong, Xiao-Dong, Fu, Jia-Ling, Wang, Yan, Nguyen, Quan Dong, Liu, Yizhi, Liu, Mugen, Li, David Wan-Cheng
Publicado 2020

Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance

por Gong, Xiao-Dong, Wang, Yan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Nie, Qian, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Xiao, Yuan, Gao, Qian, Bai, Yue-Yue, Liu, Yi-Zhi, Li, David Wan-Cheng
Publicado 2021

HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53

por Fu, Jia-Ling, Zheng, Shu-Yu, Wang, Yan, Hu, Xue-Bin, Xiao, Yuan, Wang, Jing-Miao, Zhang, Lan, Wang, Ling, Nie, Qian, Hou, Min, Bai, Yue-Yue, Gan, Yu-Wen, Liang, Xing-Miao, Xie, Liu-Liu, Li, David Wan-Cheng
Publicado 2023

PP‐1β and PP‐2Aα modulate cAMP response element‐binding protein (CREB) functions in aging control and stress response through de‐regulation of αB‐crystallin gene and p300‐p53 signa...

por Wang, Ling, Zhang, Lan, Gong, Xiao‐Dong, Fu, Jia‐Ling, Gan, Yu‐Wen, Hou, Min, Nie, Qian, Xiang, Jia‐Wen, Xiao, Yuan, Wang, Yan, Zheng, Shu‐Yu, Yang, Lan, Chen, Huimin, Xiang, Meng‐Qing, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2021

Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses

por Liu, Fang‐Yuan, Fu, Jia‐Ling, Wang, Ling, Nie, Qian, Luo, Zhongwen, Hou, Min, Yang, Yuan, Gong, Xiao‐Dong, Wang, Yan, Xiao, Yuan, Xiang, Jiawen, Hu, Xuebin, Zhang, Lan, Wu, Mingxing, Chen, Weirong, Cheng, Bing, Luo, Lixia, Zhang, Xinyu, Liu, Xialin, Zheng, Danying, Huang, Shengsong, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2020

The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax

por Nie, Qian, Chen, Huimin, Zou, Ming, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Luo, Zhongwen, Gong, Xiao-Dong, Fu, Jia-Ling, Wang, Yan, Zheng, Shu-Yu, Xiao, Yuan, Gan, Yu-Wen, Gao, Qian, Bai, Yue-Yue, Wang, Jing-Miao, Zhang, Lan, Tang, Xiang-Cheng, Hu, Xuebin, Gong, Lili, Liu, Yizhi, Li, David Wan-Cheng
Publicado 2021

MYPT1/PP1‐Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial–Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes

por Zhang, Lan, Wang, Ling, Hu, Xue‐Bin, Hou, Min, Xiao, Yuan, Xiang, Jia‐Wen, Xie, Jie, Chen, Zhi‐Gang, Yang, Tian‐Heng, Nie, Qian, Fu, Jia‐Ling, Wang, Yan, Zheng, Shu‐Yu, Liu, Yun‐Fei, Gan, Yu‐Wen, Gao, Qian, Bai, Yue‐Yue, Wang, Jing‐Miao, Qi, Rui‐Li, Zou, Ming, Ke, Qin, Zhu, Xing‐Fei, Gong, Lili, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2022