G(2)Retro as a two-step graph generative models for retrosynthesis prediction

por Chen, Ziqi, Ayinde, Oluwatosin R., Fuchs, James R., Sun, Huan, Ning, Xia
Publicado 2023

Efficacy of quorum sensing and growth inhibitors alone and in combination against avian pathogenic Escherichia coli infection in chickens

por Helmy, Yosra A., Kathayat, Dipak, Closs, Gary, Galgozy, Katie, Fuchs, James R., Rajashekara, Gireesh
Publicado 2023

Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica

por Moshiri, Jasmine, Kaur, Darpan, Hambira, Chido M., Sandala, Jenna L., Koopman, Jacob A., Fuchs, James R., Gunn, John S.
Publicado 2018

Discovery of novel small molecule modulators of Clavibacter michiganensis subsp. michiganensis

por Xu, Xiulan, Kumar, Anand, Deblais, Loïc, Pina-Mimbela, Ruby, Nislow, Corey, Fuchs, James R., Miller, Sally A., Rajashekara, Gireesh
Publicado 2015

Trichormamides A and B with Antiproliferative Activity from the Cultured Freshwater Cyanobacterium Trichormus sp. UIC 10339

por Luo, Shangwen, Krunic, Aleksej, Kang, Hahk-Soo, Chen, Wei-Lun, Woodard, John L., Fuchs, James R., Swanson, Steven M., Orjala, Jimmy
Publicado 2014

STAT3 as a potential therapeutic target in ALDH(+) and CD44(+)/CD24(+) stem cell-like pancreatic cancer cells

por Lin, Li, Jou, David, Wang, Yina, Ma, Haiyan, Liu, Tianshu, Fuchs, James, Li, Pui-Kai, Lü, Jiagao, Li, Chenglong, Lin, Jiayuh
Publicado 2016

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens

por Helmy, Yosra A., Kathayat, Dipak, Deblais, Loic, Srivastava, Vishal, Closs, Gary, Tokarski, Robert J., Ayinde, Oluwatosin, Fuchs, James R., Rajashekara, Gireesh
Publicado 2022

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

por Cen, Ling, Hutzen, Brian, Ball, Sarah, DeAngelis, Stephanie, Chen, Chun-Liang, Fuchs, James R, Li, Chenglong, Li, Pui-Kai, Lin, Jiayuh
Publicado 2009

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

por Zahid, M. Shamim Hasan, Johnson, Monica M., Tokarski, Robert J., Satoskar, Abhay R., Fuchs, James R., Bachelder, Eric M., Ainslie, Kristy M.
Publicado 2019

Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir

por Bester, Stephanie M., Adu-Ampratwum, Daniel, Annamalai, Arun S., Wei, Guochao, Briganti, Lorenzo, Murphy, Bridget C., Haney, Reed, Fuchs, James R., Kvaratskhelia, Mamuka
Publicado 2022

Cholangiocarcinoma cells secrete soluble factors that activate Jak/STAT signal transduction and promote MDSC expansion

por Yang, Jennifer, Keenan, Kaitlin, Mace, Thomas, Ferren, Matthew, Bekaii-Saab, Tanios, Fuchs, James, Schwartz, Eric, Li, Chenglong, Pui-Kai Li, Jiayuh Lin, Lesinski, Gregory
Publicado 2014

Novel Anti-Campylobacter Compounds Identified Using High Throughput Screening of a Pre-selected Enriched Small Molecules Library

por Kumar, Anand, Drozd, Mary, Pina-Mimbela, Ruby, Xu, Xiulan, Helmy, Yosra A., Antwi, Janet, Fuchs, James R., Nislow, Corey, Templeton, Jillian, Blackall, Patrick J., Rajashekara, Gireesh
Publicado 2016

Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling

por Wu, Xiaoqing, Tang, Wenhua, Marquez, Rebecca T., Li, Ke, Highfill, Chad A., He, Fengtian, Lian, Jiqin, Lin, Jiayuh, Fuchs, James R., Ji, Min, Li, Ling, Xu, Liang
Publicado 2016

Identification and Optimization of a Novel HIV-1 Integrase Inhibitor

por Adu-Ampratwum, Daniel, Pan, Yuhan, Koneru, Pratibha C., Antwi, Janet, Hoyte, Ashley C., Kessl, Jacques, Griffin, Patrick R., Kvaratskhelia, Mamuka, Fuchs, James R., Larue, Ross C.
Publicado 2022

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

por Lin, Li, Deangelis, Stephanie, Foust, Elizabeth, Fuchs, James, Li, Chenglong, Li, Pui-Kai, Schwartz, Eric B, Lesinski, Gregory B, Benson, Don, Lü, Jiagao, Hoyt, Dale, Lin, Jiayuh
Publicado 2010

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

por Fossey, Stacey L, Bear, Misty D, Lin, Jiayuh, Li, Chenglong, Schwartz, Eric B, Li, Pui-Kai, Fuchs, James R, Fenger, Joelle, Kisseberth, William C, London, Cheryl A
Publicado 2011

A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

por Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskhelia, Mamuka
Publicado 2014

Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of...

por Sattu, Kamaraj, Hochgräfe, Falko, Wu, Jianmin, Umapathy, Ganesh, Schönherr, Christina, Ruuth, Kristina, Chand, Damini, Witek, Barbara, Fuchs, James, Li, Pui-Kai, Hugosson, Fredrik, Daly, Roger J, Palmer, Ruth H, Hallberg, Bengt
Publicado 2013

HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site...

por Wang, Hao, Jurado, Kellie A., Wu, Xiaolin, Shun, Ming-Chieh, Li, Xiang, Ferris, Andrea L., Smith, Steven J., Patel, Pratiq A., Fuchs, James R., Cherepanov, Peter, Kvaratskhelia, Mamuka, Hughes, Stephen H., Engelman, Alan
Publicado 2012

Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines

por Bill, Matthew A., Nicholas, Courtney, Mace, Thomas A., Etter, Jonathan P., Li, Chenglong, Schwartz, Eric B., Fuchs, James R., Young, Gregory S., Lin, Li, Lin, Jiayuh, He, Lei, Phelps, Mitch, Li, Pui-Kai, Lesinski, Gregory B.
Publicado 2012