Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies

por Fuchs, Sebastian P, Desrosiers, Ronald C
Publicado 2016

Recombinant AAV Vectors for Enhanced Expression of Authentic IgG

por Fuchs, Sebastian P., Martinez-Navio, José M., Gao, Guangping, Desrosiers, Ronald C.
Publicado 2016

Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys

por Fuchs, Sebastian P., Martinez-Navio, José M., Rakasz, Eva G., Gao, Guangping, Desrosiers, Ronald C.
Publicado 2019

Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity

por Termini, James M., Martinez-Navio, José M., Gao, Guangping, Fuchs, Sebastian P., Desrosiers, Ronald C.
Publicado 2020

AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity

por Fuchs, Sebastian P., Martinez-Navio, José M., Piatak, Michael, Lifson, Jeffrey D., Gao, Guangping, Desrosiers, Ronald C.
Publicado 2015

Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV

por Martinez-Navio, José M., Fuchs, Sebastian P., Mendes, Desiree E., Rakasz, Eva G., Gao, Guangping, Lifson, Jeffrey D., Desrosiers, Ronald C.
Publicado 2020

High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes

por Gardner, Matthew R., Mendes, Desiree E., Muniz, Claudia P., Martinez-Navio, José M., Fuchs, Sebastian P., Gao, Guangping, Desrosiers, Ronald C.
Publicado 2022

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies

por Gardner, Matthew R., Fetzer, Ina, Kattenhorn, Lisa M., Davis-Gardner, Meredith E., Zhou, Amber S., Alfant, Barnett, Weber, Jesse A., Kondur, Hema R., Martinez-Navio, Jose M., Fuchs, Sebastian P., Desrosiers, Ronald C., Gao, Guangping, Lifson, Jeffrey D., Farzan, Michael
Publicado 2019

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

por Pedreño-Lopez, Nuria, Dang, Christine M., Rosen, Brandon C., Ricciardi, Michael J., Bailey, Varian K., Gutman, Martin J., Gonzalez-Nieto, Lucas, Pauthner, Matthias G., Le, Khoa, Song, Ge, Andrabi, Raiees, Weisgrau, Kim L., Pomplun, Nicholas, Martinez-Navio, José M., Fuchs, Sebastian P., Wrammert, Jens, Rakasz, Eva G., Lifson, Jeffrey D., Martins, Mauricio A., Burton, Dennis R., Watkins, David I., Magnani, Diogo M.
Publicado 2020

A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

por Magnani, Diogo M., Silveira, Cassia G. T., Rosen, Brandon C., Ricciardi, Michael J., Pedreño-Lopez, Núria, Gutman, Martin J., Bailey, Varian K., Maxwell, Helen S., Domingues, Aline, Gonzalez-Nieto, Lucas, Avelino-Silva, Vivian I., Trindade, Mateus, Nogueira, Juliana, Oliveira, Consuelo S., Maestri, Alvino, Felix, Alvina Clara, Levi, José Eduardo, Nogueira, Mauricio L., Martins, Mauricio A., Martinez-Navio, José M., Fuchs, Sebastian P., Whitehead, Stephen S., Burton, Dennis R., Desrosiers, Ronald C., Kallas, Esper G., Watkins, David I.
Publicado 2017

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

por Gardner, Matthew R., Kattenhorn, Lisa M., Kondur, Hema R., von Schaewen, Markus, Dorfman, Tatyana, Chiang, Jessica J., Haworth, Kevin G., Decker, Julie M., Alpert, Michael D., Bailey, Charles C., Neale, Ernest S., Fellinger, Christoph H., Joshi, Vinita R., Fuchs, Sebastian P., Martinez-Navio, Jose M., Quinlan, Brian D., Yao, Annie Y., Mouquet, Hugo, Gorman, Jason, Zhang, Baoshan, Poignard, Pascal, Nussenzweig, Michel C., Burton, Dennis R., Kwong, Peter D., Piatak, Michael, Lifson, Jeffrey D., Gao, Guangping, Desrosiers, Ronald C., Evans, David T., Hahn, Beatrice H., Ploss, Alexander, Cannon, Paula M., Seaman, Michael S., Farzan, Michael
Publicado 2015