Opportunities for Ferroptosis in Cancer Therapy

por Fujihara, Kenji M., Zhang, Bonnie Z., Clemons, Nicholas J.
Publicado 2021

Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

por Milne, Julia V., Zhang, Bonnie Z., Fujihara, Kenji M., Dawar, Swati, Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2021

The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism

por Jackson, Thomas D., Hock, Daniella H., Fujihara, Kenji M., Palmer, Catherine S., Frazier, Ann E., Low, Yau C., Kang, Yilin, Ang, Ching-Seng, Clemons, Nicholas J., Thorburn, David R., Stroud, David A., Stojanovski, Diana
Publicado 2021

Loss of SMAD4 Is Sufficient to Promote Tumorigenesis in a Model of Dysplastic Barrett’s Esophagus

por Gotovac, Jovana R., Kader, Tanjina, Milne, Julia V., Fujihara, Kenji M., Lara-Gonzalez, Luis E., Gorringe, Kylie L., Kalimuthu, Sangeetha N., Jayawardana, Madawa W., Duong, Cuong P., Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2021

Potential Clinical Utility of a Targeted Circulating Tumor DNA Assay in Esophageal Adenocarcinoma

por Cabalag, Carlos S., Yates, Michael, Corrales, Mariana Benitez, Yeh, Paul, Wong, Stephen Q., Zhang, Bonnie Z., Fujihara, Kenji M., Chong, Lynn, Hii, Michael W., Dawson, Sarah-Jane, Phillips, Wayne A., Duong, Cuong P., Clemons, Nicholas J.
Publicado 2022

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

por Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.
Publicado 2021

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

por Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.
Publicado 2022

Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module

por Jackson, Thomas D., Crameri, Jordan J., Muellner-Wong, Linden, Frazier, Ann E., Palmer, Catherine S., Formosa, Luke E., Hock, Daniella H., Fujihara, Kenji M., Stait, Tegan, Sharpe, Alice J., Thorburn, David R., Ryan, Michael T., Stroud, David A., Stojanovski, Diana
Publicado 2022

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

por Kang, Yilin, Anderson, Alexander J, Jackson, Thomas Daniel, Palmer, Catherine S, De Souza, David P, Fujihara, Kenji M, Stait, Tegan, Frazier, Ann E, Clemons, Nicholas J, Tull, Deidreia, Thorburn, David R, McConville, Malcolm J, Ryan, Michael T, Stroud, David A, Stojanovski, Diana
Publicado 2019

Correction: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

por Kang, Yilin, Anderson, Alexander J, Jackson, Thomas Daniel, Palmer, Catherine S, De Souza, David P, Fujihara, Kenji M, Stait, Tegan, Frazier, Ann E, Clemons, Nicholas J, Tull, Deidreia, Thorburn, David R, McConville, Malcolm J, Ryan, Michael T, Stroud, David A, Stojanovski, Diana
Publicado 2020

A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death

por Ceder, Sophia, Eriksson, Sofi E, Cheteh, Emarndeena H, Dawar, Swati, Corrales Benitez, Mariana, Bykov, Vladimir J N, Fujihara, Kenji M, Grandin, Mélodie, Li, Xiaodun, Ramm, Susanne, Behrenbruch, Corina, Simpson, Kaylene J, Hollande, Frédéric, Abrahmsen, Lars, Clemons, Nicholas J, Wiman, Klas G
Publicado 2020

The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density

por Cheasley, Dane, Devereux, Lisa, Hughes, Siobhan, Nickson, Carolyn, Procopio, Pietro, Lee, Grant, Li, Na, Pridmore, Vicki, Elder, Kenneth, Bruce Mann, G., Kader, Tanjina, Rowley, Simone M., Fox, Stephen B., Byrne, David, Saunders, Hugo, Fujihara, Kenji M., Lim, Belle, Gorringe, Kylie L., Campbell, Ian G.
Publicado 2020

Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer

por Cabalag, Carlos S., Prall, Owen W. J., Ciciulla, John, Galea, Laurence A., Thio, Niko, Jayawardana, Madawa, Leong, Trishe Y. M., Milne, Julia V., Fujihara, Kenji M., Chong, Lynn, Hii, Michael W., Arnau, Gisela Mir, Neeson, Paul J., Phillips, Wayne A., Duong, Cuong P., Clemons, Nicholas J.
Publicado 2022

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

por Fujihara, Kenji M., Zhang, Bonnie Z., Jackson, Thomas D., Ogunkola, Moses O., Nijagal, Brunda, Milne, Julia V., Sallman, David A., Ang, Ching-Seng, Nikolic, Iva, Kearney, Conor J., Hogg, Simon J., Cabalag, Carlos S., Sutton, Vivien R., Watt, Sally, Fujihara, Asuka T., Trapani, Joseph A., Simpson, Kaylene J., Stojanovski, Diana, Leimkühler, Silke, Haupt, Sue, Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2022