Inside the Mucosal Immune System

por McGhee, Jerry R., Fujihashi, Kohtaro
Publicado 2012

Functional Transforming Growth Factor-β Receptor Type II Expression by CD4(+) T Cells in Peyer's Patches Is Essential for Oral Tolerance Induction

por Gilbert, Rebekah S., Kobayashi, Ryoki, Sekine, Shinichi, Fujihashi, Kohtaro
Publicado 2011

Mucosal vaccines: wisdom from now and then

por Kiyono, Hiroshi, Yuki, Yoshikazu, Nakahashi-Ouchida, Rika, Fujihashi, Kohtaro
Publicado 2021

Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivali...

por Koyanagi, Kayo, Kataoka, Kosuke, Yoshimatsu, Hideki, Fujihashi, Kohtaro, Miyake, Tatsuro
Publicado 2023

Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses

por Pais, Roshan, Omosun, Yusuf, Igietseme, Joseph U., Fujihashi, Kohtaro, Eko, Francis O.
Publicado 2019

Respiratory FimA-Specific Secretory IgA Antibodies Upregulated by DC-Targeting Nasal Double DNA Adjuvant Are Essential for Elimination of Porphyromonas gingivalis

por Kataoka, Kosuke, Kawabata, Shigetada, Koyanagi, Kayo, Hashimoto, Yoshiya, Miyake, Tatsuro, Fujihashi, Kohtaro
Publicado 2021

A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the “Antigen Capsid-Incorporation” strategy

por Gu, Linlin, Krendelchtchikova, Valentina, Krendelchtchikov, Alexandre, Oster, Robert A, Fujihashi, Kohtaro, Matthews, Qiana L
Publicado 2014

Hapten-induced Colitis Is Associated with Colonic Patch Hypertrophy and T Helper Cell 2–Type Responses

por Dohi, Taeko, Fujihashi, Kohtaro, Rennert, Paul D., Iwatani, Koichi, Kiyono, Hiroshi, McGhee, Jerry R.
Publicado 1999

Oral-Nasopharyngeal Dendritic Cells Mediate T Cell-Independent IgA Class Switching on B-1 B Cells

por Kataoka, Kosuke, Fujihashi, Keiko, Terao, Yutaka, Gilbert, Rebekah S., Sekine, Shinichi, Kobayashi, Ryoki, Fukuyama, Yoshiko, Kawabata, Shigetada, Fujihashi, Kohtaro
Publicado 2011

Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice

por Pais, Roshan, Omosun, Yusuf, He, Qing, Blas-Machado, Uriel, Black, Carolyn, Igietseme, Joseph U., Fujihashi, Kohtaro, Eko, Francis O.
Publicado 2017

A Molecular Mucosal Adjuvant To Enhance Immunity Against Pneumococcal Infection In The Elderly

por Fukuyama, Yoshiko, Ikeda, Yorihiko, Ohori, Junichiro, Sugita, Gen, Aso, Kazuyoshi, Fujihashi, Keiko, Briles, David E., McGhee, Jerry R., Fujihashi, Kohtaro
Publicado 2015

Mutants in the ADP-ribosyltransferase Cleft of Cholera Toxin Lack Diarrheagenicity but Retain Adjuvanticity

por Yamamoto, Shingo, Takeda, Yoshifumi, Yamamoto, Masafumi, Kurazono, Hisao, Imaoka, Koichi, Yamamoto, Miho, Fujihashi, Kohtaro, Noda, Masatoshi, Kiyono, Hiroshi, McGhee, Jerry R.
Publicado 1997

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

por Ippolito, Gregory C., Schelonka, Robert L., Zemlin, Michael, Ivanov, Ivaylo I., Kobayashi, Ryoki, Zemlin, Cosima, Gartland, G. Larry, Nitschke, Lars, Pelkonen, Jukka, Fujihashi, Kohtaro, Rajewsky, Klaus, Schroeder, Harry W.
Publicado 2006

Adipose-Derived Mesenchymal Stem Cells Restore Impaired Mucosal Immune Responses in Aged Mice

por Aso, Kazuyoshi, Tsuruhara, Akitoshi, Takagaki, Kentaro, Oki, Katsuyuki, Ota, Megumi, Nose, Yasuhiro, Tanemura, Hideki, Urushihata, Naoki, Sasanuma, Jinichi, Sano, Masayuki, Hirano, Atsuyuki, Aso, Rio, McGhee, Jerry R., Fujihashi, Kohtaro
Publicado 2016

Induction of Mucosal IgA–Mediated Protective Immunity Against Nontypeable Haemophilus influenzae Infection by a Cationic Nanogel–Based P6 Nasal Vaccine

por Nakahashi-Ouchida, Rika, Mori, Hiromi, Yuki, Yoshikazu, Umemoto, Shingo, Hirano, Takashi, Uchida, Yohei, Machita, Tomonori, Yamanoue, Tomoyuki, Sawada, Shin-ichi, Suzuki, Masashi, Fujihashi, Kohtaro, Akiyoshi, Kazunari, Kurono, Yuichi, Kiyono, Hiroshi
Publicado 2022

Potential Roles of CCR5(+) CCR6(+) Dendritic Cells Induced by Nasal Ovalbumin plus Flt3 Ligand Expressing Adenovirus for Mucosal IgA Responses

por Fukuyama, Yoshiko, Tokuhara, Daisuke, Sekine, Shinichi, Aso, Kazuyoshi, Kataoka, Kosuke, Davydova, Julia, Yamamoto, Masato, Gilbert, Rebekah S., Tokuhara, Yuka, Fujihashi, Keiko, Kunisawa, Jun, Yuki, Yoshikazu, Kiyono, Hiroshi, McGhee, Jerry R., Fujihashi, Kohtaro
Publicado 2013

Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine

por Sasou, Ai, Yuki, Yoshikazu, Honma, Ayaka, Sugiura, Kotomi, Kashima, Koji, Kozuka-Hata, Hiroko, Nojima, Masanori, Oyama, Masaaki, Kurokawa, Shiho, Maruyama, Shinichi, Kuroda, Masaharu, Tanoue, Shinjiro, Takamatsu, Narushi, Fujihashi, Kohtaro, Goto, Eiji, Kiyono, Hiroshi
Publicado 2021

Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus

por Sasou, Ai, Yuki, Yoshikazu, Kurokawa, Shiho, Sato, Shintaro, Goda, Yuki, Uchida, Masao, Matsumoto, Naomi, Sagara, Hiroshi, Watanabe, Yuji, Kuroda, Masaharu, Sakon, Naomi, Sugiura, Kotomi, Nakahashi-Ouchida, Rika, Ushijima, Hiroshi, Fujihashi, Kohtaro, Kiyono, Hiroshi
Publicado 2021

Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents

por Umemoto, Shingo, Nakahashi-Ouchida, Rika, Yuki, Yoshikazu, Kurokawa, Shiho, Machita, Tomonori, Uchida, Yohei, Mori, Hiromi, Yamanoue, Tomoyuki, Shibata, Takehiko, Sawada, Shin-ichi, Ishige, Kazuya, Hirano, Takashi, Fujihashi, Kohtaro, Akiyoshi, Kazunari, Kurashima, Yosuke, Tokuhara, Daisuke, Ernst, Peter B, Suzuki, Masashi, Kiyono, Hiroshi
Publicado 2023

Id2-, RORγt-, and LTβR-independent initiation of lymphoid organogenesis in ocular immunity

por Nagatake, Takahiro, Fukuyama, Satoshi, Kim, Dong-Young, Goda, Kaoru, Igarashi, Osamu, Sato, Shintaro, Nochi, Tomonori, Sagara, Hiroshi, Yokota, Yoshifumi, Jetten, Anton M., Kaisho, Tsuneyasu, Akira, Shizuo, Mimuro, Hitomi, Sasakawa, Chihiro, Fukui, Yoshinori, Fujihashi, Kohtaro, Akiyama, Taishin, Inoue, Jun-ichiro, Penninger, Josef M., Kunisawa, Jun, Kiyono, Hiroshi
Publicado 2009