Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID

por Sasaguri, Hiroki, Nagata, Kenichi, Sekiguchi, Misaki, Fujioka, Ryo, Matsuba, Yukio, Hashimoto, Shoko, Sato, Kaori, Kurup, Deepika, Yokota, Takanori, Saido, Takaomi C.
Publicado 2018

A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide

por Sato, Kaori, Watamura, Naoto, Fujioka, Ryo, Mihira, Naomi, Sekiguchi, Misaki, Nagata, Kenichi, Ohshima, Toshio, Saito, Takashi, Saido, Takaomi C., Sasaguri, Hiroki
Publicado 2021

An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities

por Watamura, Naoto, Sato, Kaori, Shiihashi, Gen, Iwasaki, Ayami, Kamano, Naoko, Takahashi, Mika, Sekiguchi, Misaki, Mihira, Naomi, Fujioka, Ryo, Nagata, Kenichi, Hashimoto, Shoko, Saito, Takashi, Ohshima, Toshio, Saido, Takaomi C., Sasaguri, Hiroki
Publicado 2022

Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis

por Jiang, Richeng, Smailovic, Una, Haytural, Hazal, Tijms, Betty M., Li, Hao, Haret, Robert Mihai, Shevchenko, Ganna, Chen, Gefei, Abelein, Axel, Gobom, Johan, Frykman, Susanne, Sekiguchi, Misaki, Fujioka, Ryo, Watamura, Naoto, Sasaguri, Hiroki, Nyström, Sofie, Hammarström, Per, Saido, Takaomi C., Jelic, Vesna, Syvänen, Stina, Zetterberg, Henrik, Winblad, Bengt, Bergquist, Jonas, Visser, Pieter Jelle, Nilsson, Per
Publicado 2022