Discovery of TAK-272: A Novel, Potent, and Orally Active Renin Inhibitor

por Imaeda, Yasuhiro, Tokuhara, Hidekazu, Fukase, Yoshiyuki, Kanagawa, Ray, Kajimoto, Yumiko, Kusumoto, Keiji, Kondo, Mitsuyo, Snell, Gyorgy, Behnke, Craig A., Kuroita, Takanobu
Publicado 2016

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action

por Steinman, Jonathan B, Santarossa, Cristina C, Miller, Rand M, Yu, Lola S, Serpinskaya, Anna S, Furukawa, Hideki, Morimoto, Sachie, Tanaka, Yuta, Nishitani, Mitsuyoshi, Asano, Moriteru, Zalyte, Ruta, Ondrus, Alison E, Johnson, Alex G, Ye, Fan, Nachury, Maxence V, Fukase, Yoshiyuki, Aso, Kazuyoshi, Foley, Michael A, Gelfand, Vladimir I, Chen, James K, Carter, Andrew P, Kapoor, Tarun M
Publicado 2017