Tiny giants of gene regulation: experimental strategies for microRNA functional studies

por Steinkraus, Bruno R., Toegel, Markus, Fulga, Tudor A.
Publicado 2016

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

por Ferry, Quentin R. V., Lyutova, Radostina, Fulga, Tudor A.
Publicado 2017

Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors

por Baeumler, Toni A., Ahmed, Ahmed Ashour, Fulga, Tudor A.
Publicado 2017

Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms

por Loya, Carlos M., Lu, Cecilia S., Van Vactor, David, Fulga, Tudor A.
Publicado 2009

The Drosophila homologue of MEGF8 is essential for early development

por Lloyd, Deborah L., Toegel, Markus, Fulga, Tudor A., Wilkie, Andrew O. M.
Publicado 2018

MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

por Goodwin, Patricia R., Meng, Alice, Moore, Jessie, Hobin, Michael, Fulga, Tudor A., Van Vactor, David, Griffith, Leslie C.
Publicado 2018

A multiplexable TALE-based binary expression system for in vivo cellular interaction studies

por Toegel, Markus, Azzam, Ghows, Lee, Eunice Y., Knapp, David J. H. F., Tan, Ying, Fa, Ming, Fulga, Tudor A.
Publicado 2017

Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression

por Knapp, David J. H. F., Michaels, Yale S., Jamilly, Max, Ferry, Quentin R. V., Barbosa, Hector, Milne, Thomas A., Fulga, Tudor A.
Publicado 2019

MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells

por Mugat, Bruno, Akkouche, Abdou, Serrano, Vincent, Armenise, Claudia, Li, Blaise, Brun, Christine, Fulga, Tudor A., Van Vactor, David, Pélisson, Alain, Chambeyron, Séverine
Publicado 2015

Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

por Khurana, Vikram, Elson-Schwab, Ilan, Fulga, Tudor A., Sharp, Katherine A., Loewen, Carin A., Mulkearns, Erin, Tyynelä, Jaana, Scherzer, Clemens R., Feany, Mel B.
Publicado 2010

miR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons

por Pathania, Manavendra, Torres-Reveron, Juan, Yan, Lily, Kimura, Tomoki, Lin, Tiffany V., Gordon, Valerie, Teng, Zhao-Qian, Zhao, Xinyu, Fulga, Tudor A., Van Vactor, David, Bordey, Angélique
Publicado 2012

MicroRNAs Regulate Multiple Aspects of Locomotor Behavior in Drosophila

por Donelson, Nathan C., Dixit, Richa, Pichardo-Casas, Israel, Chiu, Eva Y., Ohman, Robert T., Slawson, Justin B., Klein, Mason, Fulga, Tudor A., Van Vactor, David, Griffith, Leslie C.
Publicado 2019

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells

por McNeill, Elizabeth M., Warinner, Chloe, Alkins, Stephen, Taylor, Alicia, Heggeness, Hansine, DeLuca, Todd F., Fulga, Tudor A., Wall, Dennis P., Griffith, Leslie C., Van Vactor, David
Publicado 2020

Modeling Spinal Muscular Atrophy in Drosophila

por Chang, Howard Chia-Hao, Dimlich, Douglas N., Yokokura, Takakazu, Mukherjee, Ashim, Kankel, Mark W., Sen, Anindya, Sridhar, Vasanthi, Fulga, Tudor A., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
Publicado 2008

ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts

por Valletta, Simona, Dolatshad, Hamid, Bartenstein, Matthias, Yip, Bon Ham, Bello, Erica, Gordon, Shanisha, Yu, Yiting, Shaw, Jacqueline, Roy, Swagata, Scifo, Laura, Schuh, Anna, Pellagatti, Andrea, Fulga, Tudor A., Verma, Amit, Boultwood, Jacqueline
Publicado 2015

A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes

por Harman, Joe R., Thorne, Ross, Jamilly, Max, Tapia, Marta, Crump, Nicholas T., Rice, Siobhan, Beveridge, Ryan, Morrissey, Edward, de Bruijn, Marella F.T.R., Roberts, Irene, Roy, Anindita, Fulga, Tudor A., Milne, Thomas A.
Publicado 2021

Understanding functional miRNA–target interactions in vivo by site-specific genome engineering

por Bassett, Andrew R., Azzam, Ghows, Wheatley, Lucy, Tibbit, Charlotte, Rajakumar, Timothy, McGowan, Simon, Stanger, Nathan, Ewels, Philip Andrew, Taylor, Stephen, Ponting, Chris P., Liu, Ji-Long, Sauka-Spengler, Tatjana, Fulga, Tudor A.
Publicado 2014

Precise tuning of gene expression levels in mammalian cells

por Michaels, Yale S., Barnkob, Mike B., Barbosa, Hector, Baeumler, Toni A., Thompson, Mary K., Andre, Violaine, Colin-York, Huw, Fritzsche, Marco, Gileadi, Uzi, Sheppard, Hilary M., Knapp, David J. H. F., Milne, Thomas A., Cerundolo, Vincenzo, Fulga, Tudor A.
Publicado 2019

Addendum: Precise tuning of gene expression levels in mammalian cells

por Michaels, Yale S., Barnkob, Mike B., Barbosa, Hector, Baeumler, Toni A., Thompson, Mary K., Andre, Violaine, Colin-York, Huw, Fritzsche, Marco, Gileadi, Uzi, Sheppard, Hilary M., Knapp, David J. H. F., Milne, Thomas A., Cerundolo, Vincenzo, Fulga, Tudor A.
Publicado 2019

A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs

por Fulga, Tudor A., McNeill, Elizabeth M., Binari, Richard, Yelick, Julia, Blanche, Alexandra, Booker, Matthew, Steinkraus, Bruno R., Schnall-Levin, Michael, Zhao, Yong, DeLuca, Todd, Bejarano, Fernando, Han, Zhe, Lai, Eric C., Wall, Dennis P., Perrimon, Norbert, Van Vactor, David
Publicado 2015