Immunotherapeutic Approaches in Malignant Pleural Mesothelioma

por Terenziani, Rita, Zoppi, Silvia, Fumarola, Claudia, Alfieri, Roberta, Bonelli, Mara
Publicado 2021

Reprogramming of Lipid Metabolism in Lung Cancer: An Overview with Focus on EGFR-Mutated Non-Small Cell Lung Cancer

por Eltayeb, Kamal, La Monica, Silvia, Tiseo, Marcello, Alfieri, Roberta, Fumarola, Claudia
Publicado 2022

Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells

por Cretella, Daniele, Fumarola, Claudia, Bonelli, Mara, Alfieri, Roberta, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Galetti, Maricla, Generali, Daniele, Petronini, Pier Giorgio
Publicado 2019

The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells

por Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio
Publicado 2018

Dual Inhibition of CDK4/6 and PI3K/AKT/mTOR Signaling Impairs Energy Metabolism in MPM Cancer Cells

por Bonelli, Mara, Terenziani, Rita, Zoppi, Silvia, Fumarola, Claudia, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Petronini, Pier Giorgio
Publicado 2020

Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines

por Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara A., Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Galetti, Maricla, Bertolini, Patrizia, Missale, Gabriele, Petronini, Pier Giorgio
Publicado 2020

Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators

por Volta, Francesco, La Monica, Silvia, Leonetti, Alessandro, Gnetti, Letizia, Bonelli, Mara, Cavazzoni, Andrea, Fumarola, Claudia, Galetti, Maricla, Eltayeb, Kamal, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2023

Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines

por La Monica, Silvia, Cretella, Daniele, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Digiacomo, Graziana, Flammini, Lisa, Barocelli, Elisabetta, Minari, Roberta, Naldi, Nadia, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2017

Novel Activity of a Synthetic Decapeptide Against Toxoplasma gondii Tachyzoites

por Giovati, Laura, Santinoli, Claudia, Mangia, Carlo, Vismarra, Alice, Belletti, Silvana, D’Adda, Tiziana, Fumarola, Claudia, Ciociola, Tecla, Bacci, Cristina, Magliani, Walter, Polonelli, Luciano, Conti, Stefania, Kramer, Laura H.
Publicado 2018

Efficacy of the CDK4/6 Dual Inhibitor Abemaciclib in EGFR-Mutated NSCLC Cell Lines with Different Resistance Mechanisms to Osimertinib

por La Monica, Silvia, Fumarola, Claudia, Cretella, Daniele, Bonelli, Mara, Minari, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Volta, Francesco, Mancini, Maicol, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2020

CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells

por Terenziani, Rita, Galetti, Maricla, La Monica, Silvia, Fumarola, Claudia, Zoppi, Silvia, Alfieri, Roberta, Digiacomo, Graziana, Cavazzoni, Andrea, Cavallo, Delia, Corradi, Massimo, Tiseo, Marcello, Petronini, Pier Giorgio, Bonelli, Mara
Publicado 2022

CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells

por Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Galetti, Maricla, Terenziani, Rita, Eltayeb, Kamal, Volta, Francesco, Zoppi, Silvia, Bertolini, Patrizia, Missale, Gabriele, Alfieri, Roberta, Petronini, Pier Giorgio
Publicado 2022

Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

por Galetti, Maricla, Petronini, Pier Giorgio, Fumarola, Claudia, Cretella, Daniele, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Saccani, Francesca, Caffarra, Cristina, Andreoli, Roberta, Mutti, Antonio, Tiseo, Marcello, Ardizzoni, Andrea, Alfieri, Roberta R.
Publicado 2015

Pemetrexed Enhances Membrane PD-L1 Expression and Potentiates T Cell-Mediated Cytotoxicity by Anti-PD-L1 Antibody Therapy in Non-Small-Cell Lung Cancer

por Cavazzoni, Andrea, Digiacomo, Graziana, Alfieri, Roberta, La Monica, Silvia, Fumarola, Claudia, Galetti, Maricla, Bonelli, Mara, Cretella, Daniele, Barili, Valeria, Zecca, Alessandra, Giovannetti, Elisa, Fiorentino, Michelangelo, Tiseo, Marcello, Petronini, Pier Giorgio, Ardizzoni, Andrea
Publicado 2020

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell L...

por Fumarola, Claudia, Bozza, Nicole, Castelli, Riccardo, Ferlenghi, Francesca, Marseglia, Giuseppe, Lodola, Alessio, Bonelli, Mara, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Minari, Roberta, Galetti, Maricla, Tiseo, Marcello, Ardizzoni, Andrea, Mor, Marco, Petronini, Pier Giorgio
Publicado 2019

Gefitinib Inhibits Invasive Phenotype and Epithelial-Mesenchymal Transition in Drug-Resistant NSCLC Cells with MET Amplification

por La Monica, Silvia, Caffarra, Cristina, Saccani, Francesca, Galvani, Elena, Galetti, Maricla, Fumarola, Claudia, Bonelli, Mara, Cavazzoni, Andrea, Cretella, Daniele, Sirangelo, Rita, Gatti, Rita, Tiseo, Marcello, Ardizzoni, Andrea, Giovannetti, Elisa, Petronini, Pier Giorgio, Alfieri, Roberta R.
Publicado 2013

Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance

por Cretella, Daniele, Saccani, Francesca, Quaini, Federico, Frati, Caterina, Lagrasta, Costanza, Bonelli, Mara, Caffarra, Cristina, Cavazzoni, Andrea, Fumarola, Claudia, Galetti, Maricla, La Monica, Silvia, Ampollini, Luca, Tiseo, Marcello, Ardizzoni, Andrea, Petronini, Pier Giorgio, Alfieri, Roberta R
Publicado 2014

Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism

por Fumarola, Claudia, Cretella, Daniele, La Monica, Silvia, Bonelli, Mara A., Alfieri, Roberta, Caffarra, Cristina, Quaini, Federico, Madeddu, Denise, Falco, Angela, Cavazzoni, Andrea, Digiacomo, Graziana, Mazzaschi, Giulia, Vivo, Valentina, Barocelli, Elisabetta, Tiseo, Marcello, Petronini, Pier Giorgio, Ardizzoni, Andrea
Publicado 2017

Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines

por Alfieri, Roberta R, Galetti, Maricla, Tramonti, Stefano, Andreoli, Roberta, Mozzoni, Paola, Cavazzoni, Andrea, Bonelli, Mara, Fumarola, Claudia, La Monica, Silvia, Galvani, Elena, De Palma, Giuseppe, Mutti, Antonio, Mor, Marco, Tiseo, Marcello, Mari, Ettore, Ardizzoni, Andrea, Petronini, Pier Giorgio
Publicado 2011

Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells()

por Bonelli, Mara A., Digiacomo, Graziana, Fumarola, Claudia, Alfieri, Roberta, Quaini, Federico, Falco, Angela, Madeddu, Denise, La Monica, Silvia, Cretella, Daniele, Ravelli, Andrea, Ulivi, Paola, Tebaldi, Michela, Calistri, Daniele, Delmonte, Angelo, Ampollini, Luca, Carbognani, Paolo, Tiseo, Marcello, Cavazzoni, Andrea, Petronini, Pier Giorgio
Publicado 2017