Toward Realistic Dosimetry In Vitro: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an In Silico Mass Balance Model

por Dimitrijevic, Dunja, Fabian, Eric, Nicol, Beate, Funk-Weyer, Dorothee, Landsiedel, Robert
Publicado 2022

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology

por Botham, Philip, Cronin, Mark T. D., Currie, Richard, Doe, John, Funk-Weyer, Dorothee, Gant, Timothy W., Leist, Marcel, Marty, Sue, van Ravenzwaay, Bennard, Westmoreland, Carl
Publicado 2023

Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with ni...

por Ramirez-Hincapie, Sabina, Birk, Barbara, Ternes, Philipp, Giri, Varun, Zickgraf, Franziska Maria, Haake, Volker, Herold, Michael, Kamp, Hennicke, Driemert, Peter, Landsiedel, Robert, Richling, Elke, Funk-Weyer, Dorothee, van Ravenzwaay, Bennard
Publicado 2023

A high-throughput metabolomics in vitro platform for the characterization of hepatotoxicity

por Ramirez-Hincapie, Sabina, Birk, Barbara, Ternes, Philipp, Giri, Varun, Haake, Volker, Herold, Michael, Zickgraf, Franziska Maria, Verlohner, Andreas, Huener, Hans-Albrecht, Kamp, Hennicke, Driemert, Peter, Landsiedel, Robert, Richling, Elke, Funk-Weyer, Dorothee, van Ravenzwaay, Bennard
Publicado 2023