KPC-2 β-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate

por Mehta, Shrenik C., Furey, Ian M., Pemberton, Orville A., Boragine, David M., Chen, Yu, Palzkill, Timothy
Publicado 2020

Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 β-lactamase

por Furey, Ian M., Mehta, Shrenik C., Sankaran, Banumathi, Hu, Liya, Prasad, B.V. Venkataram, Palzkill, Timothy
Publicado 2021

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing

por Swings, Toon, Marciano, David C., Atri, Benu, Bosserman, Rachel E., Wang, Chen, Leysen, Marlies, Bonte, Camille, Schalck, Thomas, Furey, Ian, Van den Bergh, Bram, Verstraeten, Natalie, Christie, Peter J., Herman, Christophe, Lichtarge, Olivier, Michiels, Jan
Publicado 2018