Cells of Matter—In Vitro Models for Myotonic Dystrophy

por Matloka, Magdalena, Klein, Arnaud F., Rau, Frédérique, Furling, Denis
Publicado 2018

miR-7 Restores Phenotypes in Myotonic Dystrophy Muscle Cells by Repressing Hyperactivated Autophagy

por Sabater-Arcis, Maria, Bargiela, Ariadna, Furling, Denis, Artero, Ruben
Publicado 2019

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

por Hubé, Florent, Velasco, Guillaume, Rollin, Jérôme, Furling, Denis, Francastel, Claire
Publicado 2011

A CRISPR-Cas13a Based Strategy That Tracks and Degrades Toxic RNA in Myotonic Dystrophy Type 1

por Zhang, Nan, Bewick, Brittani, Xia, Guangbin, Furling, Denis, Ashizawa, Tetsuo
Publicado 2020

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle

por Koutsoulidou, Andrie, Mastroyiannopoulos, Nikolaos P, Furling, Denis, Uney, James B, Phylactou, Leonidas A
Publicado 2011

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

por Laurent, François-Xavier, Sureau, Alain, Klein, Arnaud F., Trouslard, François, Gasnier, Erwan, Furling, Denis, Marie, Joëlle
Publicado 2012

The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

por Monceau, Alexandra, Delacroix, Clément, Lemaitre, Mégane, Revet, Gaelle, Furling, Denis, Agbulut, Onnik, Klein, Arnaud, Ferry, Arnaud
Publicado 2022

Potassium currents in human myogenic cells from healthy and congenital myotonic dystrophy foetuses

por Nurowska, Ewa, Constanti, Andrew, Dworakowska, Beata, Mouly, Vincent, Furling, Denis, Lorenzon, Paola, Pietrangelo, Tiziana, Dołowy, Krzysztof, Ruzzier, Fabio
Publicado 2009

Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes

por Dastidar, Sumitava, Majumdar, Debanjana, Tipanee, Jaitip, Singh, Kshitiz, Klein, Arnaud F., Furling, Denis, Chuah, Marinee K., VandenDriessche, Thierry
Publicado 2022

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

por Roy, Pauline, Rau, Fredérique, Ochala, Julien, Messéant, Julien, Fraysse, Bodvael, Lainé, Jeanne, Agbulut, Onnik, Butler-Browne, Gillian, Furling, Denis, Ferry, Arnaud
Publicado 2016

Genome Editing of Expanded CTG Repeats within the Human DMPK Gene Reduces Nuclear RNA Foci in the Muscle of DM1 Mice

por Lo Scrudato, Mirella, Poulard, Karine, Sourd, Célia, Tomé, Stéphanie, Klein, Arnaud F., Corre, Guillaume, Huguet, Aline, Furling, Denis, Gourdon, Geneviève, Buj-Bello, Ana
Publicado 2019

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

por Alves, Sandro, Marais, Thibaut, Biferi, Maria-Grazia, Furling, Denis, Marinello, Martina, El Hachimi, Khalid, Cartier, Nathalie, Ruberg, Merle, Stevanin, Giovanni, Brice, Alexis, Barkats, Martine, Sittler, Annie
Publicado 2016

Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts

por Rizzo, Milena, Beffy, Pascale, Del Carratore, Renata, Falleni, Alessandra, Pretini, Virginia, D’Aurizio, Romina, Botta, Annalisa, Evangelista, Monica, Stoccoro, Andrea, Coppedè, Fabio, Furling, Denis, Simili, Marcella
Publicado 2018

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

por Klinck, Roscoe, Fourrier, Angélique, Thibault, Philippe, Toutant, Johanne, Durand, Mathieu, Lapointe, Elvy, Caillet-Boudin, Marie-Laure, Sergeant, Nicolas, Gourdon, Geneviève, Meola, Giovanni, Furling, Denis, Puymirat, Jack, Chabot, Benoit
Publicado 2014

Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques

por Moulay, Gilles, Lainé, Jeanne, Lemaître, Mégane, Nakamori, Masayuki, Nishino, Ichizo, Caillol, Ghislaine, Mamchaoui, Kamel, Julien, Laura, Dingli, Florent, Loew, Damarys, Bitoun, Marc, Leterrier, Christophe, Furling, Denis, Vassilopoulos, Stéphane
Publicado 2020

Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells

por Porquet, Florent, Weidong, Lin, Jehasse, Kévin, Gazon, Hélène, Kondili, Maria, Blacher, Silvia, Massotte, Laurent, Di Valentin, Emmannuel, Furling, Denis, Gillet, Nicolas Albert, Klein, Arnaud François, Seutin, Vincent, Willems, Luc
Publicado 2023

CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis

por Mérien, Antoine, Tahraoui-Bories, Julie, Cailleret, Michel, Dupont, Jean-Baptiste, Leteur, Céline, Polentes, Jérôme, Carteron, Alexandre, Polvèche, Hélène, Concordet, Jean-Paul, Pinset, Christian, Jarrige, Margot, Furling, Denis, Martinat, Cécile
Publicado 2021

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1

por Maury, Yves, Poydenot, Pauline, Brinon, Benjamin, Lesueur, Lea, Gide, Jacqueline, Roquevière, Sylvain, Côme, Julien, Polvèche, Hélène, Auboeuf, Didier, Alexandre Denis, Jérome, Pietu, Geneviève, Furling, Denis, Lechuga, Marc, Baghdoyan, Sandrine, Peschanski, Marc, Martinat, Cécile
Publicado 2018

Dysregulation of Circular RNAs in Myotonic Dystrophy Type 1

por Voellenkle, Christine, Perfetti, Alessandra, Carrara, Matteo, Fuschi, Paola, Renna, Laura Valentina, Longo, Marialucia, Sain, Simona Baghai, Cardani, Rosanna, Valaperta, Rea, Silvestri, Gabriella, Legnini, Ivano, Bozzoni, Irene, Furling, Denis, Gaetano, Carlo, Falcone, Germana, Meola, Giovanni, Martelli, Fabio
Publicado 2019

Molecular, Physiological, and Motor Performance Defects in DMSXL Mice Carrying >1,000 CTG Repeats from the Human DM1 Locus

por Huguet, Aline, Medja, Fadia, Nicole, Annie, Vignaud, Alban, Guiraud-Dogan, Céline, Ferry, Arnaud, Decostre, Valérie, Hogrel, Jean-Yves, Metzger, Friedrich, Hoeflich, Andreas, Baraibar, Martin, Gomes-Pereira, Mário, Puymirat, Jack, Bassez, Guillaume, Furling, Denis, Munnich, Arnold, Gourdon, Geneviève
Publicado 2012