The role of the bone marrow in neutrophil clearance under homeostatic conditions in the mouse

por Furze, Rebecca C., Rankin, Sara M.
Publicado 2008

The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation

por Wengner, Antje M., Pitchford, Simon C., Furze, Rebecca C., Rankin, Sara M.
Publicado 2008

A role for Rab27 in neutrophil chemotaxis and lung recruitment

por Singh, Rajesh K, Furze, Rebecca C, Birrell, Mark A, Rankin, Sara M, Hume, Alistair N, Seabra, Miguel C
Publicado 2014

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins

por Chabert, Clovis, Khochbin, Saadi, Rousseaux, Sophie, Furze, Rebecca, Smithers, Nicholas, Prinjha, Rab, Schlattner, Uwe, Pison, Christophe, Dubouchaud, Hervé
Publicado 2017

Bromodomain inhibitor I‐BET151 suppresses immune responses during fungal–immune interaction

por Domínguez‐Andrés, Jorge, Ferreira, Anaísa V, Jansen, Trees, Smithers, Nicholas, Prinjha, Rab K., Furze, Rebecca C., Netea, Mihai G.
Publicado 2019

Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

por Chabert, Clovis, Khochbin, Saadi, Rousseaux, Sophie, Veyrenc, Sylvie, Furze, Rebecca, Smithers, Nicholas, Prinjha, Rab K, Schlattner, Uwe, Pison, Christophe, Dubouchaud, Hervé
Publicado 2018

Phase 1 and preclinical profiling of ESM‐HDAC391, a myeloid‐targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia

por Furze, Rebecca C., Molnar, Judit, Parr, Nigel J., Ahmad, Faiz, Henry, Yvette, Howe, David, Singh, Rajendra, Toal, Martin, Bassil, Anna K., Bernard, Sharon G., Davis, Robert P., Gibson, Adele, Maller, N. Claire, Sharp, Catriona, Tough, David F., Prinjha, Rab K., Lewis, Huw D.
Publicado 2022

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

por Luque-Martin, Rosario, Van den Bossche, Jan, Furze, Rebecca C., Neele, Annette E., van der Velden, Saskia, Gijbels, Marion J.J., van Roomen, Cindy P.P.A., Bernard, Sharon G., de Jonge, Wouter J., Rioja, Inmaculada, Prinjha, Rab K., Lewis, Huw D., Mander, Palwinder K., de Winther, Menno P.J.
Publicado 2019

A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn’s Disease

por Elfiky, Ahmed M. I., Hageman, Ishtu L., Becker, Marte A. J., Verhoeff, Jan, Li Yim, Andrew Y. F., Joustra, Vincent W., Mulders, Lieven, Fung, Ivan, Rioja, Inmaculada, Prinjha, Rab K., Smithers, Nicholas N., Furze, Rebecca C., Mander, Palwinder K., Bell, Matthew J., Buskens, Christianne J., D’Haens, Geert R., Wildenberg, Manon E., de Jonge, Wouter J.
Publicado 2022

Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease

por Elfiky, Ahmed M I, Ghiboub, Mohammed, Li Yim, Andrew Y F, Hageman, Ishtu L, Verhoeff, Jan, de Krijger, Manon, van Hamersveld, Patricia H P, Welting, Olaf, Admiraal, Iris, Rahman, Shafaque, Garcia-Vallejo, Juan J, Wildenberg, Manon E, Tomlinson, Laura, Gregory, Richard, Rioja, Inmaculada, Prinjha, Rab K, Furze, Rebecca C, Lewis, Huw D, Mander, Palwinder K, Heinsbroek, Sigrid E M, Bell, Matthew J, de Jonge, Wouter J
Publicado 2021

Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo

por Falcinelli, Shane D., Peterson, Jackson J., Turner, Anne-Marie W., Irlbeck, David, Read, Jenna, Raines, Samuel L.M., James, Katherine S., Sutton, Cameron, Sanchez, Anthony, Emery, Ann, Sampey, Gavin, Ferris, Robert, Allard, Brigitte, Ghofrani, Simon, Kirchherr, Jennifer L., Baker, Caroline, Kuruc, JoAnn D., Gay, Cynthia L., James, Lindsey I., Wu, Guoxin, Zuck, Paul, Rioja, Inmaculada, Furze, Rebecca C., Prinjha, Rab K., Howell, Bonnie J., Swanstrom, Ronald, Browne, Edward P., Strahl, Brian D., Dunham, Richard M., Archin, Nancie M., Margolis, David M.
Publicado 2022