Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies

por Fusi, Nicoló, Stegle, Oliver, Lawrence, Neil D.
Publicado 2012

Warped linear mixed models for the genetic analysis of transformed phenotypes

por Fusi, Nicolo, Lippert, Christoph, Lawrence, Neil D., Stegle, Oliver
Publicado 2014

Further Improvements to Linear Mixed Models for Genome-Wide Association Studies

por Widmer, Christian, Lippert, Christoph, Weissbrod, Omer, Fusi, Nicolo, Kadie, Carl, Davidson, Robert, Listgarten, Jennifer, Heckerman, David
Publicado 2014

Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased s...

por Brockington, Alice, Ning, Ke, Heath, Paul R., Wood, Elizabeth, Kirby, Janine, Fusi, Nicolò, Lawrence, Neil, Wharton, Stephen B., Ince, Paul G., Shaw, Pamela J.
Publicado 2012

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

por Doench, John G., Fusi, Nicolo, Sullender, Meagan, Hegde, Mudra, Vaimberg, Emma W., Donovan, Katherine F., Smith, Ian, Tothova, Zuzana, Wilen, Craig, Orchard, Robert, Virgin, Herbert W., Listgarten, Jennifer, Root, David E.
Publicado 2016

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

por Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Publicado 2017

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

por Bartha, István, Carlson, Jonathan M, Brumme, Chanson J, McLaren, Paul J, Brumme, Zabrina L, John, Mina, Haas, David W, Martinez-Picado, Javier, Dalmau, Judith, López-Galíndez, Cecilio, Casado, Concepción, Rauch, Andri, Günthard, Huldrych F, Bernasconi, Enos, Vernazza, Pietro, Klimkait, Thomas, Yerly, Sabine, O’Brien, Stephen J, Listgarten, Jennifer, Pfeifer, Nico, Lippert, Christoph, Fusi, Nicolo, Kutalik, Zoltán, Allen, Todd M, Müller, Viktor, Harrigan, P Richard, Heckerman, David, Telenti, Amalio, Fellay, Jacques
Publicado 2013

Impact of Pre-adapted HIV Transmission

por Carlson, Jonathan M., Du, Victor Y., Pfeifer, Nico, Bansal, Anju, Tan, Vincent Y.F., Power, Karen, Brumme, Chanson J., Kreimer, Anat, DeZiel, Charles E., Fusi, Nicolo, Schaefer, Malinda, Brockman, Mark A., Gilmour, Jill, Price, Matt A., Kilembe, William, Haubrich, Richard, John, Mina, Mallal, Simon, Shapiro, Roger, Frater, John, Harrigan, P. Richard, Ndung’u, Thumbi, Allen, Susan, Heckerman, David, Sidney, John, Allen, Todd M., Goulder, Philip J.R., Brumme, Zabrina L., Hunter, Eric, Goepfert, Paul A.
Publicado 2016