Structure of Trypanosoma brucei glutathione synthetase: Domain and loop alterations in the catalytic cycle of a highly conserved enzyme

por Fyfe, Paul K., Alphey, Magnus S., Hunter, William N.
Publicado 2010

The structure of tubulin-binding cofactor A from Leishmania major infers a mode of association during the early stages of microtubule assembly

por Barrack, Keri L., Fyfe, Paul K., Hunter, William N.
Publicado 2015

Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity

por Dawson, Alice, Fyfe, Paul K, Gillet, Florian, Hunter, William N
Publicado 2011

Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment

por Zoltner, Martin, Fyfe, Paul K., Palmer, Tracy, Hunter, William N.
Publicado 2012

Leishmania Trypanothione Synthetase-Amidase Structure Reveals a Basis for Regulation of Conflicting Synthetic and Hydrolytic Activities

por Fyfe, Paul K., Oza, Sandra L., Fairlamb, Alan H., Hunter, William N.
Publicado 2008

Structure and Reactivity of Bacillus subtilis MenD Catalyzing the First Committed Step in Menaquinone Biosynthesis

por Dawson, Alice, Chen, Minjiao, Fyfe, Paul K., Guo, Zhihong, Hunter, William N.
Publicado 2010

Crystal structure of the C-terminal domain of tubulin-binding cofactor C from Leishmania major

por Barrack, Keri L., Fyfe, Paul K., Finney, Alex J., Hunter, William N.
Publicado 2015

Structure of Staphylococcus aureus adenylo­succinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery

por Fyfe, Paul K., Dawson, Alice, Hutchison, Marie-Theres, Cameron, Scott, Hunter, William N.
Publicado 2010

Structural insights into the assembly and activation of the IL‐27 signaling complex

por Jin, Yibo, Fyfe, Paul K, Gardner, Scott, Wilmes, Stephan, Bubeck, Doryen, Moraga, Ignacio
Publicado 2022

How the structure of the large subunit controls function in an oxygen-tolerant [NiFe]-hydrogenase

por Bowman, Lisa, Flanagan, Lindsey, Fyfe, Paul K., Parkin, Alison, Hunter, William N., Sargent, Frank
Publicado 2014

Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site

por Barrack, Keri L., Tulloch, Lindsay B., Burke, Lynsey-Ann, Fyfe, Paul K., Hunter, William N.
Publicado 2010

The architecture of Trypanosoma brucei tubulin-binding cofactor B and implications for function

por Fleming, Jennifer R, Morgan, Rachel E, Fyfe, Paul K, Kelly, Sharon M, Hunter, William N
Publicado 2013

Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment

por O’Rourke, Patrick EF, Kalinowska-Tłuścik, Justyna, Fyfe, Paul K, Dawson, Alice, Hunter, William N
Publicado 2014

Structure of Leishmania major cysteine synthase

por Fyfe, Paul K., Westrop, Gareth D., Ramos, Tania, Müller, Sylke, Coombs, Graham H., Hunter, William N.
Publicado 2012

The Architecture of EssB, an Integral Membrane Component of the Type VII Secretion System

por Zoltner, Martin, Norman, David G., Fyfe, Paul K., El Mkami, Hassane, Palmer, Tracy, Hunter, William N.
Publicado 2013

Pseudomonas aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme

por O'Rourke, Patrick E. F., Eadsforth, Thomas C., Fyfe, Paul K., Shepherd, Sharon M., Hunter, William N.
Publicado 2011

Structure and activity of ChiX: a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens

por Owen, Richard A., Fyfe, Paul K., Lodge, Adam, Biboy, Jacob, Vollmer, Waldemar, Hunter, William N., Sargent, Frank
Publicado 2018

EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system

por Zoltner, Martin, Ng, Wui M.A.V., Money, Jillian J., Fyfe, Paul K., Kneuper, Holger, Palmer, Tracy, Hunter, William N.
Publicado 2016

Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate

por Dawson, Alice, Gibellini, Federica, Sienkiewicz, Natasha, Tulloch, Lindsay B, Fyfe, Paul K, McLuskey, Karen, Fairlamb, Alan H, Hunter, William N
Publicado 2006

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

por Martinez-Fabregas, Jonathan, Wilmes, Stephan, Wang, Luopin, Hafer, Maximillian, Pohler, Elizabeth, Lokau, Juliane, Garbers, Christoph, Cozzani, Adeline, Fyfe, Paul K, Piehler, Jacob, Kazemian, Majid, Mitra, Suman, Moraga, Ignacio
Publicado 2019