Can Mechanistic Static Models for Drug-Drug Interactions Support Regulatory Filing for Study Waivers and Label Recommendations?

por Gomez-Mantilla, Jose David, Huang, Fenglei, Peters, Sheila Annie
Publicado 2023

Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions

por Hanke, Nina, Gómez-Mantilla, José David, Ishiguro, Naoki, Stopfer, Peter, Nock, Valerie
Publicado 2021

Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Prediction...

por Loer, Helena Leonie Hanae, Türk, Denise, Gómez-Mantilla, José David, Selzer, Dominik, Lehr, Thorsten
Publicado 2022

A systems pharmacology model for inflammatory bowel disease

por Balbas-Martinez, Violeta, Ruiz-Cerdá, Leire, Irurzun-Arana, Itziar, González-García, Ignacio, Vermeulen, An, Gómez-Mantilla, José David, Trocóniz, Iñaki F.
Publicado 2018

A quantitative systems pharmacology model for acute viral hepatitis B

por Asín-Prieto, Eduardo, Parra-Guillen, Zinnia P., Gómez Mantilla, José David, Vandenbossche, Joris, Stuyckens, Kim, de Trixhe, Xavier Woot, Perez-Ruixo, Juan José, Troconiz, Iñaki F.
Publicado 2021