Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches

por Güler, Rezan, Svedmark, Siri Flemming, Abouzayed, Ayman, Orlova, Anna, Löfblom, John
Publicado 2020

Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

por Vorobyeva, Anzhelika, Sсhulga, Alexey, Konovalova, Elena, Güler, Rezan, Mitran, Bogdan, Garousi, Javad, Rinne, Sara, Löfblom, John, Orlova, Anna, Deyev, Sergey, Tolmachev, Vladimir
Publicado 2019

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

por Gast, Veronica, Sandegren, Anna, Dunås, Finn, Ekblad, Siri, Güler, Rezan, Thorén, Staffan, Tous Mohedano, Marta, Molin, Mikael, Engqvist, Martin K. M., Siewers, Verena
Publicado 2022

Optimal composition and position of histidine-containing tags improves biodistribution of (99m)Tc-labeled DARPin G3

por Vorobyeva, Anzhelika, Schulga, Alexey, Konovalova, Elena, Güler, Rezan, Löfblom, John, Sandström, Mattias, Garousi, Javad, Chernov, Vladimir, Bragina, Olga, Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey M.
Publicado 2019

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

por Mitran, Bogdan, Güler, Rezan, Roche, Francis P., Lindström, Elin, Selvaraju, Ram Kumar, Fleetwood, Filippa, Rinne, Sara S., Claesson-Welsh, Lena, Tolmachev, Vladimir, Ståhl, Stefan, Orlova, Anna, Löfblom, John
Publicado 2018

Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis

por Liu, Yongsheng, Güler, Rezan, Liao, Yunqi, Vorobyeva, Anzhelika, Widmark, Olof, Meuleman, Theodorus J., Koijen, Anna, van den Bos, Leendert J., Naasz, Robert, Bodenko, Vitalina, Orlova, Anna, Ekblad, Caroline, Tolmachev, Vladimir, Frejd, Fredrik Y.
Publicado 2022