A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells

por Mender, Ilgen, Gryaznov, Sergei, Shay, Jerry W.
Publicado 2015

DIPG-05. EVALUATION OF TELOMERE-MODIFYING COMPOUND THIO AS A RADIOSENSITIZER AND IMMUNOMODULATOR TO TREAT DIPG

por Mishra, Deepak, Umaru, Banlanjo, Kumar, Shiva Senthil, Gryaznov, Sergei, Drissi, Rachid
Publicado 2023

Imetelstat (a telomerase antagonist) exerts off-target effects on the cytoskeleton

por MENDER, ILGEN, SENTURK, SERIF, OZGUNES, NURIMAN, AKCALI, K. CAN, KLETSAS, DIMITRIS, GRYAZNOV, SERGEI, CAN, ALP, SHAY, JERRY W., DIKMEN, Z. GUNNUR
Publicado 2013

Telomere Shortening Sensitizes Cancer Cells to Selected Cytotoxic Agents: In Vitro and In Vivo Studies and Putative Mechanisms

por Uziel, Orit, Beery, Einat, Dronichev, Vladimir, Samocha, Katty, Gryaznov, Sergei, Weiss, Lola, Slavin, Shimon, Kushnir, Michal, Nordenberg, Yardena, Rabinowitz, Claudette, Rinkevich, Baruch, Zehavi, Tania, Lahav, Meir
Publicado 2010

Targeting TLR9 agonists to secondary lymphoid organs induces potent immune responses against HBV infection

por Ushach, Irina, Zhu, Ren, Rosler, Elen, Pandey, Rajendra K., De Costa, N. Tilani S., Pourshahian, Soheil, Han, Qinglin, Li, Chris, Beigelman, Leonid, Gryaznov, Sergei M., Yun, Theodore
Publicado 2022

Telomerase Contributes to Fludarabine Resistance in Primary Human Leukemic Lymphocytes

por Shawi, May, Chu, Tsz Wai, Martinez-Marignac, Veronica, Yu, Y., Gryaznov, Sergei M., Johnston, James B., Lees-Miller, Susan P., Assouline, Sarit E., Autexier, Chantal, Aloyz, Raquel
Publicado 2013

Targeting homologous recombination and telomerase in Barrett’s adenocarcinoma: Impact on telomere maintenance, genomic instability, and tumor growth

por Lu, Renquan, Pal, Jagannath, Buon, Leutz, Nanjappa, Puru, Shi, Jialan, Fulciniti, Mariateresa, Tai, Yu-Tzu, Guo, Lin, Yu, Min, Gryaznov, Sergei, Munshi, Nikhil C., Shammas, Masood A.
Publicado 2013

Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma

por Ferrandon, Sylvain, Malleval, Céline, El Hamdani, Badia, Battiston-Montagne, Priscillia, Bolbos, Radu, Langlois, Jean-Baptiste, Manas, Patrick, Gryaznov, Sergei M, Alphonse, Gersende, Honnorat, Jérôme, Rodriguez-Lafrasse, Claire, Poncet, Delphine
Publicado 2015

Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma

por Mender, Ilgen, Siteni, Silvia, Barron, Summer, Flusche, Ann Marie, Kubota, Naoto, Yu, Chunhua, Cornelius, Crystal, Tedone, Enzo, Maziveyi, Mazvita, Grichuk, Anthony, Venkateswaran, Niranjan, Conacci-Sorrell, Maralice, Hoshida, Yujin, Kang, Rui, Tang, Daolin, Gryaznov, Sergei, Shay, Jerry W.
Publicado 2023