An affibody-adalimumab hybrid blocks combined IL-6 and TNF-triggered serum amyloid A secretion in vivo

por Yu, Feifan, Gudmundsdotter, Lindvi, Akal, Anastassja, Gunneriusson, Elin, Frejd, Fredrik, Nygren, Per-Åke
Publicado 2014

Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity

por Fleetwood, Filippa, Klint, Susanne, Hanze, Martin, Gunneriusson, Elin, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John
Publicado 2014

Imaging of CAIX-expressing xenografts in vivo using (99m)Tc-HEHEHE-ZCAIX:1 Affibody molecule

por HONARVAR, HADIS, GAROUSI, JAVAD, GUNNERIUSSON, ELIN, HÖIDÉN-GUTHENBERG, INGMARIE, ALTAI, MOHAMED, WIDSTRÖM, CHARLES, TOLMACHEV, VLADIMIR, FREJD, FREDRIK Y.
Publicado 2014

Identification of proteins that specifically recognize and bind protofibrillar aggregates of amyloid-β

por Wahlberg, Elisabet, Rahman, M. Mahafuzur, Lindberg, Hanna, Gunneriusson, Elin, Schmuck, Benjamin, Lendel, Christofer, Sandgren, Mats, Löfblom, John, Ståhl, Stefan, Härd, Torleif
Publicado 2017

Affibody-Mediated Sequestration of Amyloid β Demonstrates Preventive Efficacy in a Transgenic Alzheimer’s Disease Mouse Model

por Boutajangout, Allal, Lindberg, Hanna, Awwad, Abdulaziz, Paul, Arun, Baitalmal, Rabaa, Almokyad, Ismail, Höidén-Guthenberg, Ingmarie, Gunneriusson, Elin, Frejd, Fredrik Y., Härd, Torleif, Löfblom, John, Ståhl, Stefan, Wisniewski, Thomas
Publicado 2019

Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis

por Klint, Susanne, Feldwisch, Joachim, Gudmundsdotter, Lindvi, Dillner Bergstedt, Karin, Gunneriusson, Elin, Höidén Guthenberg, Ingmarie, Wennborg, Anders, Nyborg, Andrew C., Kamboj, Amol P., Peloso, Paul M., Bejker, David, Frejd, Fredrik Y.
Publicado 2023