N‐terminal alterations turn the gut hormone GLP‐2 into an antagonist with gradual loss of GLP‐2 receptor selectivity towards more GLP‐1 receptor interaction

por Gabe, Maria Buur Nordskov, Gasbjerg, Lærke Smidt, Gadgaard, Sarina, Lindquist, Peter, Holst, Jens Juul, Rosenkilde, Mette Marie
Publicado 2022

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long‐term impairment of the GIP sys...

por Gabe, Maria Buur Nordskov, van der Velden, Wijnand J. C., Gadgaard, Sarina, Smit, Florent Xavier, Hartmann, Bolette, Bräuner‐Osborne, Hans, Rosenkilde, Mette Marie
Publicado 2019

Glucose‐dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet‐fed mice

por Boer, Geke Aline, Hunt, Jenna Elizabeth, Gabe, Maria Buur Nordskov, Windeløv, Johanne Agerlin, Sparre‐Ulrich, Alexander Hovard, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette Marie
Publicado 2022