The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disea...

por Berquez, Marine, Gadsby, Jonathan R., Festa, Beatrice Paola, Butler, Richard, Jackson, Stephen P., Berno, Valeria, Luciani, Alessandro, Devuyst, Olivier, Gallop, Jennifer L.
Publicado 2020

Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres

por Goldspink, Deborah A., Rookyard, Chris, Tyrrell, Benjamin J., Gadsby, Jonathan, Perkins, James, Lund, Elizabeth K., Galjart, Niels, Thomas, Paul, Wileman, Tom, Mogensen, Mette M.
Publicado 2017

Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature

por Daste, Frederic, Walrant, Astrid, Holst, Mikkel R., Gadsby, Jonathan R., Mason, Julia, Lee, Ji-Eun, Brook, Daniel, Mettlen, Marcel, Larsson, Elin, Lee, Steven F., Lundmark, Richard, Gallop, Jennifer L.
Publicado 2017

Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation

por Dobramysl, Ulrich, Jarsch, Iris Katharina, Inoue, Yoshiko, Shimo, Hanae, Richier, Benjamin, Gadsby, Jonathan R., Mason, Julia, Szałapak, Alicja, Ioannou, Pantelis Savvas, Correia, Guilherme Pereira, Walrant, Astrid, Butler, Richard, Hannezo, Edouard, Simons, Benjamin D., Gallop, Jennifer L.
Publicado 2021

A direct role for SNX9 in the biogenesis of filopodia

por Jarsch, Iris K., Gadsby, Jonathan R., Nuccitelli, Annalisa, Mason, Julia, Shimo, Hanae, Pilloux, Ludovic, Marzook, Bishara, Mulvey, Claire M., Dobramysl, Ulrich, Bradshaw, Charles R., Lilley, Kathryn S., Hayward, Richard D., Vaughan, Tristan J., Dobson, Claire L., Gallop, Jennifer L.
Publicado 2020