A Bayesian Method to Incorporate Hundreds of Functional Characteristics with Association Evidence to Improve Variant Prioritization

por Gagliano, Sarah A., Barnes, Michael R., Weale, Michael E., Knight, Jo
Publicado 2014

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

por Gagliano, Sarah A., Paterson, Andrew D., Weale, Michael E., Knight, Jo
Publicado 2015

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants

por Gagliano, Sarah A., Ravji, Reena, Barnes, Michael R., Weale, Michael E., Knight, Jo
Publicado 2015

Relative impact of indels versus SNPs on complex disease

por Gagliano, Sarah A., Sengupta, Sebanti, Sidore, Carlo, Maschio, Andrea, Cucca, Francesco, Schlessinger, David, Abecasis, Gonçalo R.
Publicado 2018

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

por Gagliano, Sarah A., Pouget, Jennie G., Hardy, John, Knight, Jo, Barnes, Michael R., Ryten, Mina, Weale, Michael E.
Publicado 2016

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

por Hughes, Craig D., Choi, Minee L., Ryten, Mina, Hopkins, Lee, Drews, Anna, Botía, Juan A., Iljina, Maria, Rodrigues, Margarida, Gagliano, Sarah A., Gandhi, Sonia, Bryant, Clare, Klenerman, David
Publicado 2018

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

por Zhou, Wei, Nielsen, Jonas B., Fritsche, Lars G., Dey, Rounak, Gabrielsen, Maiken E., Wolford, Brooke N., LeFaive, Jonathon, VandeHaar, Peter, Gagliano, Sarah A., Gifford, Aliya, Bastarache, Lisa A., Wei, Wei-Qi, Denny, Joshua C., Lin, Maoxuan, Hveem, Kristian, Kang, Hyun Min, Abecasis, Goncalo R., Willer, Cristen J., Lee, Seunggeun
Publicado 2018

Long‐ and short‐term outcomes in renal allografts with deceased donors: A large recipient and donor genome‐wide association study

por Hernandez‐Fuentes, Maria P., Franklin, Christopher, Rebollo‐Mesa, Irene, Mollon, Jennifer, Delaney, Florence, Perucha, Esperanza, Stapleton, Caragh, Borrows, Richard, Byrne, Catherine, Cavalleri, Gianpiero, Clarke, Brendan, Clatworthy, Menna, Feehally, John, Fuggle, Susan, Gagliano, Sarah A., Griffin, Sian, Hammad, Abdul, Higgins, Robert, Jardine, Alan, Keogan, Mary, Leach, Timothy, MacPhee, Iain, Mark, Patrick B., Marsh, James, Maxwell, Peter, McKane, William, McLean, Adam, Newstead, Charles, Augustine, Titus, Phelan, Paul, Powis, Steve, Rowe, Peter, Sheerin, Neil, Solomon, Ellen, Stephens, Henry, Thuraisingham, Raj, Trembath, Richard, Topham, Peter, Vaughan, Robert, Sacks, Steven H., Conlon, Peter, Opelz, Gerhard, Soranzo, Nicole, Weale, Michael E., Lord, Graham M.
Publicado 2018