Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

por Narayanan, Chitra, Gagné, Donald, Reynolds, Kimberly A., Doucet, Nicolas
Publicado 2017

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

por Narayanan, Chitra, Bernard, David N., Bafna, Khushboo, Gagné, Donald, Agarwal, Pratul K., Doucet, Nicolas
Publicado 2018

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells

por Grosset, Andrée-Anne, Labrie, Marilyne, Gagné, Donald, Vladoiu, Maria-Claudia, Gaboury, Louis, Doucet, Nicolas, St-Pierre, Yves
Publicado 2014

Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin

por Vladoiu, Maria Claudia, Labrie, Marilyne, Létourneau, Myriam, Egesborg, Philippe, Gagné, Donald, Billard, Étienne, Grosset, Andrée-Anne, Doucet, Nicolas, Chatenet, David, St-Pierre, Yves
Publicado 2015

The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function

por Gobeil, Sophie M. C., Ebert, Maximillian C. C. J. C., Park, Jaeok, Gagné, Donald, Doucet, Nicolas, Berghuis, Albert M., Pleiss, Jürgen, Pelletier, Joelle N.
Publicado 2019

Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies

por Gagné, Donald, Sarker, Muzaddid, Gingras, Geneviève, Hodgson, Derek J., Frahm, Grant, Creskey, Marybeth, Lorbetskie, Barry, Bigelow, Stewart, Wang, Jun, Zhang, Xu, Johnston, Michael J. W., Lu, Huixin, Aubin, Yves
Publicado 2023