mRNA trans‐splicing in gene therapy for genetic diseases

por Berger, Adeline, Maire, Séverine, Gaillard, Marie‐Claude, Sahel, José‐Alain, Hantraye, Philippe, Bemelmans, Alexis‐Pierre
Publicado 2016

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

por Benchoua, Alexandra, Trioulier, Yaël, Diguet, Elsa, Malgorn, Carole, Gaillard, Marie-Claude, Dufour, Noelle, Elalouf, Jean-Marc, Krajewski, Stan, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2008

Zero Echo Time (17)O-MRI Reveals Decreased Cerebral Metabolic Rate of Oxygen Consumption in a Murine Model of Amyloidosis

por Baligand, Celine, Barret, Olivier, Tourais, Amélie, Pérot, Jean-Baptiste, Thenadey, Didier, Petit, Fanny, Liot, Géraldine, Gaillard, Marie-Claude, Flament, Julien, Dhenain, Marc, Valette, Julien
Publicado 2021

Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing

por Cambon, Karine, Zimmer, Virginie, Martineau, Sylvain, Gaillard, Marie-Claude, Jarrige, Margot, Bugi, Aurore, Miniarikova, Jana, Rey, Maria, Hassig, Raymonde, Dufour, Noelle, Auregan, Gwenaelle, Hantraye, Philippe, Perrier, Anselme L., Déglon, Nicole
Publicado 2017

Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease

por Francelle, Laetitia, Galvan, Laurie, Gaillard, Marie-Claude, Guillermier, Martine, Houitte, Diane, Bonvento, Gilles, Petit, Fanny, Jan, Caroline, Dufour, Noëlle, Hantraye, Philippe, Elalouf, Jean-Marc, De Chaldée, Michel, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2015

IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates

por Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, Van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe
Publicado 2013

Correction: IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates

por Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, Van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe
Publicado 2013

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat

por d’Orange, Marie, Aurégan, Gwénaelle, Cheramy, Dimitri, Gaudin-Guérif, Mylène, Lieger, Sarah, Guillermier, Martine, Stimmer, Lev, Joséphine, Charlène, Hérard, Anne-Sophie, Gaillard, Marie-Claude, Petit, Fanny, Kiessling, Maren Christine, Schmitz, Christoph, Colin, Morvane, Buée, Luc, Panayi, Fany, Diguet, Elsa, Brouillet, Emmanuel, Hantraye, Philippe, Bemelmans, Alexis-Pierre, Cambon, Karine
Publicado 2018

The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo

por Cresto, Noémie, Gardier, Camille, Gaillard, Marie-Claude, Gubinelli, Francesco, Roost, Pauline, Molina, Daniela, Josephine, Charlène, Dufour, Noëlle, Auregan, Gwenaëlle, Guillermier, Martine, Bernier, Suéva, Jan, Caroline, Gipchtein, Pauline, Hantraye, Philippe, Chartier-Harlin, Marie-Christine, Bonvento, Gilles, Van Camp, Nadja, Taymans, Jean-Marc, Cambon, Karine, Liot, Géraldine, Bemelmans, Alexis-Pierre, Brouillet, Emmanuel
Publicado 2021

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

por Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, de Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, de Chaldée, Michel, Auregan, Gwenaelle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Merienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme L, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2018

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

por Ceyzériat, Kelly, Ben Haim, Lucile, Denizot, Audrey, Pommier, Dylan, Matos, Marco, Guillemaud, Océane, Palomares, Marie-Ange, Abjean, Laurene, Petit, Fanny, Gipchtein, Pauline, Gaillard, Marie-Claude, Guillermier, Martine, Bernier, Sueva, Gaudin, Mylène, Aurégan, Gwenaëlle, Joséphine, Charlène, Déchamps, Nathalie, Veran, Julien, Langlais, Valentin, Cambon, Karine, Bemelmans, Alexis P, Baijer, Jan, Bonvento, Gilles, Dhenain, Marc, Deleuze, Jean-François, Oliet, Stéphane H R, Brouillet, Emmanuel, Hantraye, Philippe, Carrillo-de Sauvage, Maria-Angeles, Olaso, Robert, Panatier, Aude, Escartin, Carole
Publicado 2018