Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans

por Ling, I-Fang, Golde, Todd E., Galasko, Douglas R., Koo, Edward H.
Publicado 2015

Effect of TTP488 in patients with mild to moderate Alzheimer’s disease

por Burstein, Aaron H, Grimes, Imogene, Galasko, Douglas R, Aisen, Paul S, Sabbagh, Marwan, Mjalli, Adnan MM
Publicado 2014

Potential implications of practice effects in Alzheimer's disease prevention trials

por Jacobs, Diane M., Ard, M. Colin, Salmon, David P., Galasko, Douglas R., Bondi, Mark W., Edland, Steven D.
Publicado 2017

Unmasking the benefits of donepezil via psychometrically precise identification of mild cognitive impairment: A secondary analysis of the ADCS vitamin E and donepezil in MCI study

por Edmonds, Emily C., Ard, M. Colin, Edland, Steven D., Galasko, Douglas R., Salmon, David P., Bondi, Mark W.
Publicado 2017

Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males

por Sandau, Ursula S., McFarland, Trevor J., Smith, Sierra J., Galasko, Douglas R., Quinn, Joseph F., Saugstad, Julie A.
Publicado 2022

Dedifferentiation and neuronal repression define familial Alzheimer’s disease

por Caldwell, Andrew B., Liu, Qing, Schroth, Gary P., Galasko, Douglas R., Yuan, Shauna H., Wagner, Steven L., Subramaniam, Shankar
Publicado 2020

Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines

por Thomas, Kelsey R., Bangen, Katherine J., Edmonds, Emily C., Weigand, Alexandra J., Walker, Kayla S., Bondi, Mark W., Galasko, Douglas R.
Publicado 2021

The neuroinflammatory marker sTNFR2 relates to worse cognition and tau in women across the Alzheimer's disease spectrum

por Bernier, Rachel A., Banks, Sarah J., Panizzon, Matthew S., Andrews, Murray J., Jacobs, Emily G., Galasko, Douglas R., Shepherd, Alyx L., Akassoglou, Katerina, Sundermann, Erin E.
Publicado 2022

Transcriptomic profiling of sporadic Alzheimer’s disease patients

por Caldwell, Andrew B., Anantharaman, Balaji G., Ramachandran, Srinivasan, Nguyen, Phuong, Liu, Qing, Trinh, Ivy, Galasko, Douglas R., Desplats, Paula A., Wagner, Steven L., Subramaniam, Shankar
Publicado 2022

Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease

por Valdes, Phoebe, Henry, Kenneth W., Fitzgerald, Michael Q., Muralidharan, Koushik, Caldwell, Andrew B., Ramachandran, Srinivasan, Goldstein, Lawrence S. B., Mobley, William C., Galasko, Douglas R., Subramaniam, Shankar
Publicado 2023

Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor and Cognitive Function in Non-Demented Subjects

por Li, Ge, Peskind, Elaine R., Millard, Steven P., Chi, Peter, Sokal, Izabela, Yu, Chang-En, Bekris, Lynn M., Raskind, Murray A., Galasko, Douglas R., Montine, Thomas J.
Publicado 2009

Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

por Caldwell, Andrew B., Liu, Qing, Zhang, Can, Schroth, Gary P., Galasko, Douglas R., Rynearson, Kevin D., Tanzi, Rudolph E., Yuan, Shauna H., Wagner, Steven L., Subramaniam, Shankar
Publicado 2022

Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults

por Li, Ge, Shofer, Jane B., Petrie, Eric C., Yu, Chang-En, Wilkinson, Charles W., Figlewicz, Dianne P., Shutes-David, Andrew, Zhang, Jing, Montine, Thomas J., Raskind, Murray A., Quinn, Joseph F., Galasko, Douglas R., Peskind, Elaine R.
Publicado 2017

Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study

por Marshall, Gad A., Sikkes, Sietske A. M., Amariglio, Rebecca E., Gatchel, Jennifer R., Rentz, Dorene M., Johnson, Keith A., Langford, Oliver, Sun, Chung‐Kai, Donohue, Michael C., Raman, Rema, Aisen, Paul S., Sperling, Reisa A., Galasko, Douglas R.
Publicado 2020

A user's guide for α‐synuclein biomarker studies in biological fluids: Perianalytical considerations

por Mollenhauer, Brit, Batrla, Richard, El‐Agnaf, Omar, Galasko, Douglas R., Lashuel, Hilal A., Merchant, Kalpana M., Shaw, Lesley M., Selkoe, Dennis J., Umek, Robert, Vanderstichele, Hugo, Zetterberg, Henrik, Zhang, Jing, Caspell‐Garcia, Chelsea, Coffey, Chris, Hutten, Samantha J., Frasier, Mark, Taylor, Peggy
Publicado 2017

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

por Prots, Iryna, Grosch, Janina, Brazdis, Razvan-Marius, Simmnacher, Katrin, Veber, Vanesa, Havlicek, Steven, Hannappel, Christian, Krach, Florian, Krumbiegel, Mandy, Schütz, Oliver, Reis, André, Wrasidlo, Wolfgang, Galasko, Douglas R., Groemer, Teja W., Masliah, Eliezer, Schlötzer-Schrehardt, Ursula, Xiang, Wei, Winkler, Jürgen, Winner, Beate
Publicado 2018

CD4(+) T cells contribute to neurodegeneration in Lewy body dementia

por Gate, David, Tapp, Emma, Leventhal, Olivia, Shahid, Marian, Nonninger, Tim J., Yang, Andrew C., Strempfl, Katharina, Unger, Michael S., Fehlmann, Tobias, Oh, Hamilton, Channappa, Divya, Henderson, Victor W., Keller, Andreas, Aigner, Ludwig, Galasko, Douglas R., Davis, Mark M., Poston, Kathleen L., Wyss-Coray, Tony
Publicado 2021

A cerebrospinal fluid microRNA signature as biomarker for glioblastoma

por Akers, Johnny C., Hua, Wei, Li, Hongying, Ramakrishnan, Valya, Yang, Zixiao, Quan, Kai, Zhu, Wei, Li, Jie, Figueroa, Javier, Hirshman, Brian R., Miller, Brittney, Piccioni, David, Ringel, Florian, Komotar, Ricardo, Messer, Karen, Galasko, Douglas R., Hochberg, Fred, Mao, Ying, Carter, Bob S., Chen, Clark C.
Publicado 2017

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

por Perrin, Richard J., Craig-Schapiro, Rebecca, Malone, James P., Shah, Aarti R., Gilmore, Petra, Davis, Alan E., Roe, Catherine M., Peskind, Elaine R., Li, Ge, Galasko, Douglas R., Clark, Christopher M., Quinn, Joseph F., Kaye, Jeffrey A., Morris, John C., Holtzman, David M., Townsend, R. Reid, Fagan, Anne M.
Publicado 2011

Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease

por Irwin, David J., Fedler, Janel, Coffey, Christopher S., Caspell‐Garcia, Chelsea, Kang, Ju Hee, Simuni, Tanya, Foroud, Tatiana, Toga, Arthur W., Tanner, Caroline M., Kieburtz, Karl, Chahine, Lana M., Reimer, Alyssa, Hutten, Samantha, Weintraub, Daniel, Mollenhauer, Brit, Galasko, Douglas R., Siderowf, Andrew, Marek, Kenneth, Trojanowski, John Q., Shaw, Leslie M.
Publicado 2020