A Novel Receptor Tyrosine Kinase Switch Promotes Gastrointestinal Stromal Tumor Drug Resistance

por Boichuk, Sergei, Galembikova, Aigul, Dunaev, Pavel, Valeeva, Elena, Shagimardanova, Elena, Gusev, Oleg, Khaiboullina, Svetlana
Publicado 2017

Targeting of FGF-Signaling Re-Sensitizes Gastrointestinal Stromal Tumors (GIST) to Imatinib In Vitro and In Vivo

por Boichuk, Sergei, Galembikova, Aigul, Dunaev, Pavel, Micheeva, Ekaterina, Valeeva, Elena, Novikova, Maria, Khromova, Natalya, Kopnin, Pavel
Publicado 2018

Inhibition of AKT-Signaling Sensitizes Soft Tissue Sarcomas (STS) and Gastrointestinal Stromal Tumors (GIST) to Doxorubicin via Targeting of Homology-Mediated DNA Repair

por Boichuk, Sergei, Bikinieva, Firuza, Nurgatina, Ilmira, Dunaev, Pavel, Valeeva, Elena, Aukhadieva, Aida, Sabirov, Alexey, Galembikova, Aigul
Publicado 2020

Infigratinib (BGJ 398), a Pan-FGFR Inhibitor, Targets P-Glycoprotein and Increases Chemotherapeutic-Induced Mortality of Multidrug-Resistant Tumor Cells

por Boichuk, Sergei, Dunaev, Pavel, Mustafin, Ilshat, Mani, Shinjit, Syuzov, Kirill, Valeeva, Elena, Bikinieva, Firuza, Galembikova, Aigul
Publicado 2022

Computational-Based Discovery of the Anti-Cancer Activities of Pyrrole-Based Compounds Targeting the Colchicine-Binding Site of Tubulin

por Boichuk, Sergei, Syuzov, Kirill, Bikinieva, Firuza, Galembikova, Aigul, Zykova, Svetlana, Gankova, Ksenia, Igidov, Sergei, Igidov, Nazim
Publicado 2022

Establishment and Characterization of Multi-Drug Resistant p53-Negative Osteosarcoma SaOS-2 Subline

por Boichuk, Sergei, Bikinieva, Firyuza, Valeeva, Elena, Dunaev, Pavel, Vasileva, Maria, Kopnin, Pavel, Mikheeva, Ekaterina, Ivoilova, Tatyana, Mustafin, Ilshat, Galembikova, Aigul
Publicado 2023

2-APCAs, the Novel Microtubule Targeting Agents Active against Distinct Cancer Cell Lines

por Boichuk, Sergei, Galembikova, Aigul, Bikinieva, Firuza, Dunaev, Pavel, Aukhadieva, Aida, Syuzov, Kirill, Zykova, Svetlana, Igidov, Nazim, Ksenofontov, Alexander, Bocharov, Pavel
Publicado 2021

The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site

por Boichuk, Sergei, Galembikova, Aigul, Syuzov, Kirill, Dunaev, Pavel, Bikinieva, Firuza, Aukhadieva, Aida, Zykova, Svetlana, Igidov, Nazim, Gankova, Ksenia, Novikova, Maria, Kopnin, Pavel
Publicado 2021

Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations

por Boichuk, Sergei, Dunaev, Pavel, Skripova, Vera, Galembikova, Aigul, Bikinieva, Firyuza, Shagimardanova, Elena, Gazizova, Guzel, Deviatiiarov, Ruslan, Valeeva, Elena, Mikheeva, Ekaterina, Vasilyeva, Maria, Kopnin, Pavel, Strelnikov, Vladimir, Kiyamova, Ramziya
Publicado 2023

Inhibition of FGF2-Mediated Signaling in GIST—Promising Approach for Overcoming Resistance to Imatinib

por Boichuk, Sergei, Galembikova, Aigul, Mikheeva, Ekaterina, Bikinieva, Firuza, Aukhadieva, Aida, Dunaev, Pavel, Khalikov, Dinar, Petrov, Semen, Kurtasanov, Refat, Valeeva, Elena, Kireev, Igor, Dugina, Vera, Lushnikova, Anna, Novikova, Maria, Kopnin, Pavel
Publicado 2020

Unraveling the Mechanism of Platelet Aggregation Suppression by Monoterpenoids

por Nikitina, Liliya E., Pavelyev, Roman S., Gilfanov, Ilmir R., Kiselev, Sergei V., Azizova, Zulfiya R., Ksenofontov, Alexander A., Bocharov, Pavel S., Antina, Elena V., Klochkov, Vladimir V., Timerova, Ayzira F., Rakhmatullin, Ilfat Z., Ostolopovskaya, Olga V., Khelkhal, Mohammed A., Boichuk, Sergei V., Galembikova, Aigul R., Andriutsa, Natalia S., Frolova, Larisa L., Kutchin, Alexander V., Kayumov, Airat R.
Publicado 2022