Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy

por Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A., Hasa-Moreno, Adela, Farias, Santiago E., Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Sutton, Janette, Bolton, Gary, Zhou, Dahui, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L., Pons, Jaume, Rajpal, Arvind
Publicado 2015