An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models

por Xia, Wenle, Petricoin, Emanual F, Zhao, Sumin, Liu, Leihua, Osada, Takuya, Cheng, Qing, Wulfkuhle, Julia D, Gwin, William R, Yang, Xiaoyi, Gallagher, Rosa I, Bacus, Sarah, Lyerly, H Kim, Spector, Neil L
Publicado 2013

Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL

por Olshen, Adam, Wolf, Denise, Jones, Ella F., Newitt, David, van ‘t Veer, Laura J., Yau, Christina, Esserman, Laura, Wulfkuhle, Julia D., Gallagher, Rosa I., Singer, Lisa, Petricoin, Emanuel F., Hylton, Nola, Park, Catherine C.
Publicado 2017

Tumor-Specific Major Histocompatibility-II Expression Predicts Benefit to Anti–PD-1/L1 Therapy in Patients With HER2-Negative Primary Breast Cancer

por Gonzalez-Ericsson, Paula I., Wulfkhule, Julia D., Gallagher, Rosa I., Sun, Xiaopeng, Axelrod, Margaret L., Sheng, Quanhu, Luo, Na, Gomez, Henry, Sanchez, Violeta, Sanders, Melinda, Pusztai, Lajos, Petricoin, Emanuel, Blenman, Kim R.M., Balko, Justin M.
Publicado 2021

Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial

por Wolf, Denise M., Yau, Christina, Wulfkuhle, Julia, Brown-Swigart, Lamorna, Gallagher, Rosa I., Magbanua, Mark Jesus M., O’Grady, Nick, Hirst, Gillian, Asare, Smita, Tripathy, Debu, Berry, Don, Esserman, Laura, Chien, A. Jo, Petricoin, Emanuel F., van ‘t Veer, Laura
Publicado 2020

Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival

por Espina, Virginia, Mariani, Brian D., Gallagher, Rosa I., Tran, Khoa, Banks, Stacey, Wiedemann, Joy, Huryk, Heather, Mueller, Claudius, Adamo, Luana, Deng, Jianghong, Petricoin, Emanuel F., Pastore, Lucia, Zaman, Syed, Menezes, Geetha, Mize, James, Johal, Jasbir, Edmiston, Kirsten, Liotta, Lance A.
Publicado 2010

Functional Mapping of AKT Signaling and Biomarkers of Response from the FAIRLANE Trial of Neoadjuvant Ipatasertib plus Paclitaxel for Triple-Negative Breast Cancer

por Shi, Zhen, Wulfkuhle, Julia, Nowicka, Malgorzata, Gallagher, Rosa I., Saura, Cristina, Nuciforo, Paolo G., Calvo, Isabel, Andersen, Jay, Passos-Coelho, José Luis, Gil-Gil, Miguel J., Bermejo, Begoña, Pratt, Debra A., Ciruelos, Eva M., Villagrasa, Patricia, Wongchenko, Matthew J., Petricoin, Emanuel F., Oliveira, Mafalda, Isakoff, Steven J.
Publicado 2022

Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion

por Damayanti, Nur P., Saadatzadeh, M. Reza, Dobrota, Erika, Ordaz, Josue D., Bailey, Barbara J., Pandya, Pankita H., Bijangi-Vishehsaraei, Khadijeh, Shannon, Harlan E., Alfonso, Anthony, Coy, Kathy, Trowbridge, Melissa, Sinn, Anthony L., Zhang, Zhong-Yin, Gallagher, Rosa I., Wulfkuhle, Julia, Petricoin, Emanuel, Richardson, Angela M., Marshall, Mark S., Lion, Alex, Ferguson, Michael J., Balsara, Karl E., Pollok, Karen E.
Publicado 2023

Phase II trial of fulvestrant plus enzalutamide in ER+/HER2− advanced breast cancer

por Elias, Anthony D., Spoelstra, Nicole S., Staley, Alyse W., Sams, Sharon, Crump, Lyndsey S., Vidal, Gregory A., Borges, Virginia F., Kabos, Peter, Diamond, Jennifer R., Shagisultanova, Elena, Afghahi, Anosheh, Mayordomo, Jose, McSpadden, Tessa, Crawford, Gloria, D’Alessandro, Angelo, Zolman, Kathryn L., van Bokhoven, Adrie, Zhuang, Yonghua, Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin III, Emanuel F., Gao, Dexiang, Richer, Jennifer K.
Publicado 2023

PD-L1 quantification across tumor types using the reverse phase protein microarray: implications for precision medicine

por Baldelli, Elisa, Hodge, K Alex, Bellezza, Guido, Shah, Neil J, Gambara, Guido, Sidoni, Angelo, Mandarano, Martina, Ruhunusiri, Chamodya, Dunetz, Bryant, Abu-Khalaf, Maysa, Wulfkuhle, Julia, Gallagher, Rosa I, Liotta, Lance, de Bono, Johann, Mehra, Niven, Riisnaes, Ruth, Ravaggi, Antonella, Odicino, Franco, Sereni, Maria Isabella, Blackburn, Matthew, Zupa, Angela, Improta, Giuseppina, Demsko, Perry, Crino', Lucio, Ludovini, Vienna, Giaccone, Giuseppe, Petricoin, Emanuel F, Pierobon, Mariaelena
Publicado 2021

Multi‐omic molecular profiling guide’s efficacious treatment selection in refractory metastatic breast cancer: a prospective phase II clinical trial

por Pierobon, Mariaelena, Robert, Nicholas J., Northfelt, Donald W., Jahanzeb, Mohammad, Wong, Shukmei, Hodge, Kimberly A., Baldelli, Elisa, Aldrich, Jessica, Craig, David W., Liotta, Lance A., Avramovic, Sanja, Wojtusiak, Janusz, Alemi, Farrokh, Wulfkuhle, Julia D., Bellos, Angela, Gallagher, Rosa I., Arguello, David, Conrad, Amber, Kemkes, Ariane, Loesch, David M., Vocila, Linda, Dunetz, Bryant, Carpten, John D., Petricoin, Emanuel F., Anthony, Stephen P.
Publicado 2021

Integrative Multi-OMICs Identifies Therapeutic Response Biomarkers and Confirms Fidelity of Clinically Annotated, Serially Passaged Patient-Derived Xenografts Established from Prim...

por Pandya, Pankita H., Jannu, Asha Jacob, Bijangi-Vishehsaraei, Khadijeh, Dobrota, Erika, Bailey, Barbara J., Barghi, Farinaz, Shannon, Harlan E., Riyahi, Niknam, Damayanti, Nur P., Young, Courtney, Malko, Rada, Justice, Ryli, Albright, Eric, Sandusky, George E., Wurtz, L. Daniel, Collier, Christopher D., Marshall, Mark S., Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin, Emanuel F., Coy, Kathy, Trowbridge, Melissa, Sinn, Anthony L., Renbarger, Jamie L., Ferguson, Michael J., Huang, Kun, Zhang, Jie, Saadatzadeh, M. Reza, Pollok, Karen E.
Publicado 2022

Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2(+) breast cancer in the adaptively randomized I-SPY2 trial

por Clark, Amy S., Yau, Christina, Wolf, Denise M., Petricoin, Emanuel F., van ‘t Veer, Laura J., Yee, Douglas, Moulder, Stacy L., Wallace, Anne M., Chien, A. Jo, Isaacs, Claudine, Boughey, Judy C., Albain, Kathy S., Kemmer, Kathleen, Haley, Barbara B., Han, Hyo S., Forero-Torres, Andres, Elias, Anthony, Lang, Julie E., Ellis, Erin D., Yung, Rachel, Tripathy, Debu, Nanda, Rita, Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Gallagher, Rosa I., Helsten, Teresa, Roesch, Erin, Ewing, Cheryl A., Alvarado, Michael, Crane, Erin P., Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Steeg, Katherine, Asare, Adam, Matthews, Jeffrey B., Berry, Scott, Sanil, Ashish, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Schwab, Richard B., Symmans, W. Fraser, Hylton, Nola M., Berry, Donald A., Esserman, Laura J., DeMichele, Angela M.
Publicado 2021