Dual Targeting of MDM4 and FTH1 by MMRi71 for Induced Protein Degradation and p53-Independent Apoptosis in Leukemia Cells

por Lama, Rati, Galster, Samuel L., Xu, Chao, Davison, Luke W., Chemler, Sherry R., Wang, Xinjiang
Publicado 2022

Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status

por Lama, Rati, Xu, Chao, Galster, Samuel L., Querol-García, Javier, Portwood, Scott, Mavis, Cory K., Ruiz, Federico M., Martin, Diana, Wu, Jin, Giorgi, Marianna C., Bargonetti, Jill, Wang, Eunice S., Hernandez-Ilizaliturri, Francisco J., Koudelka, Gerald B., Chemler, Sherry R., Muñoz, Inés G., Wang, Xinjiang
Publicado 2022