Histone Deacetylase Inhibition Decreases Cholesterol Levels in Neuronal Cells by Modulating Key Genes in Cholesterol Synthesis, Uptake and Efflux

por Nunes, Maria João, Moutinho, Miguel, Gama, Maria João, Rodrigues, Cecília M. P., Rodrigues, Elsa
Publicado 2013

Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance

por Leonardo-Sousa, Carlota, Carvalho, Andreia Neves, Guedes, Romina A., Fernandes, Pedro M. P., Aniceto, Natália, Salvador, Jorge A. R., Gama, Maria João, Guedes, Rita C.
Publicado 2022

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk

por Moutinho, Miguel, Nunes, Maria João, Correia, Jorge C., Gama, Maria João, Castro-Caldas, Margarida, Cedazo-Minguez, Angel, Rodrigues, Cecília M. P., Björkhem, Ingemar, Ruas, Jorge L, Rodrigues, Elsa
Publicado 2016

New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies

por Guedes, Romina A., Grilo, Jorge H., Carvalho, Andreia N., Fernandes, Pedro M. P., Ressurreição, Ana S., Brito, Vanessa, Santos, Adriana O., Silvestre, Samuel, Gallerani, Eleonora, Gama, Maria João, Gavioli, Riccardo, Salvador, Jorge A. R., Guedes, Rita C.
Publicado 2023