VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria

por Tomlinson, Alice, Semblat, Jean-Philippe, Gamain, Benoît, Chêne, Arnaud
Publicado 2021

Progress and Insights Toward an Effective Placental Malaria Vaccine

por Gamain, Benoît, Chêne, Arnaud, Viebig, Nicola K., Tuikue Ndam, Nicaise, Nielsen, Morten A.
Publicado 2021

Expression and Purification of scFv(2H7)-P18F3, a Bi-Modular Fusion Protein (BMFP) Targeting Human CD20

por Brousse, Carine, Rainey, Nathan E., Desrames, Alexandra, Teillaud, Jean-Luc, Gamain, Benoît, Chêne, Arnaud
Publicado 2023

Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites

por Fernandez, Pablo, KViebig, Nicola, Dechavanne, Sébastien, Lépolard, Catherine, Gysin, Jürg, Scherf, Artur, Gamain, Benoit
Publicado 2008

VAR2CSA binding phenotype has ancient origin and arose before Plasmodium falciparum crossed to humans: implications in placental malaria vaccine design

por Gangnard, Stéphane, Chêne, Arnaud, Dechavanne, Sébastien, Srivastava, Anand, Avril, Marion, Smith, Joseph D., Gamain, Benoît
Publicado 2019

Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region

por Srivastava, Anand, Gangnard, Stéphane, Dechavanne, Sébastien, Amirat, Farroudja, Lewit Bentley, Anita, Bentley, Graham A., Gamain, Benoît
Publicado 2011

Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions

por Gangnard, Stéphane, Lewit-Bentley, Anita, Dechavanne, Sébastien, Srivastava, Anand, Amirat, Faroudja, Bentley, Graham A., Gamain, Benoît
Publicado 2015

Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of the Plasmodium falciparum VAR2CSA protein. Co...

por Vuchelen, Anneleen, Pardon, Els, Steyaert, Jan, Gamain, Benoît, Loris, Remy, van Nuland, Nico A. J., Ramboarina, Stéphanie
Publicado 2013

Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC

por Chêne, Arnaud, Gangnard, Stéphane, Guadall, Anna, Ginisty, Hervé, Leroy, Odile, Havelange, Nicolas, Viebig, Nicola K., Gamain, Benoît
Publicado 2019

Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype

por Viebig, Nicola K., Levin, Emily, Dechavanne, Sébastien, Rogerson, Stephen J., Gysin, Jürg, Smith, Joseph D., Scherf, Artur, Gamain, Benoit
Publicado 2007

Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates

por Avril, Marion, Hathaway, Marianne J., Srivastava, Anand, Dechavanne, Sébastien, Hommel, Mirja, Beeson, James G., Smith, Joseph D., Gamain, Benoît
Publicado 2011

Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

por Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Publicado 2015

Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

por Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Publicado 2016

Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain

por Nunes-Silva, Sofia, Gangnard, Stéphane, Vidal, Marta, Vuchelen, Anneleen, Dechavanne, Sebastien, Chan, Sherwin, Pardon, Els, Steyaert, Jan, Ramboarina, Stephanie, Chêne, Arnaud, Gamain, Benoît
Publicado 2014

Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria

por Tétard, Marilou, Milet, Jacqueline, Dechavanne, Sébastien, Fievet, Nadine, Dorin-Semblat, Dominique, Elion, Jacques, Fairhurst, Rick M., Deloron, Philippe, Tuikue-Ndam, Nicaise, Gamain, Benoît
Publicado 2017

Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development

por Chêne, Arnaud, Gangnard, Stéphane, Dechavanne, Célia, Dechavanne, Sebastien, Srivastava, Anand, Tétard, Marilou, Hundt, Sophia, Leroy, Odile, Havelange, Nicolas, Viebig, Nicola K., Gamain, Benoît
Publicado 2018

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

por Lansche, Christine, Dasanna, Anil K., Quadt, Katharina, Fröhlich, Benjamin, Missirlis, Dimitris, Tétard, Marilou, Gamain, Benoit, Buchholz, Bernd, Sanchez, Cecilia P., Tanaka, Motomu, Schwarz, Ulrich S., Lanzer, Michael
Publicado 2018

An Exported Kinase Family Mediates Species-Specific Erythrocyte Remodelling and Virulence in Human Malaria

por Davies, Heledd, Belda, Hugo, Broncel, Malgorzata, Ye, Xingda, Bisson, Claudine, Introini, Viola, Dorin-Semblat, Dominique, Semblat, Jean-Philippe, Tibúrcio, Marta, Gamain, Benoit, Kaforou, Myrsini, Treeck, Moritz
Publicado 2020

Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

por Chêne, Arnaud, Houard, Sophie, Nielsen, Morten A., Hundt, Sophia, D’Alessio, Flavia, Sirima, Sodiomon B., Luty, Adrian J. F., Duffy, Patrick, Leroy, Odile, Gamain, Benoit, Viebig, Nicola K.
Publicado 2016

BMFPs, a versatile therapeutic tool for redirecting a preexisting Epstein-Barr virus antibody response toward defined target cells

por Gamain, Benoît, Brousse, Carine, Rainey, Nathan E., Diallo, Béré K., Paquereau, Clara-Eva, Desrames, Alexandra, Ceputyte, Jolita, Semblat, Jean-Philippe, Bertrand, Olivier, Gangnard, Stéphane, Teillaud, Jean-Luc, Chêne, Arnaud
Publicado 2022