High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium

por Yang, Yang, Biedendieck, Rebekka, Wang, Wei, Gamer, Martin, Malten, Marco, Jahn, Dieter, Deckwer, Wolf-Dieter
Publicado 2006

Structural analysis of random transgene integration in CHO manufacturing cell lines by targeted sequencing

por Stadermann, Anna, Gamer, Martin, Fieder, Jürgen, Lindner, Benjamin, Fehrmann, Steffen, Schmidt, Moritz, Schulz, Patrick, Gorr, Ingo H.
Publicado 2022

miRNA engineering of CHO cells facilitates production of difficult‐to‐express proteins and increases success in cell line development

por Fischer, Simon, Marquart, Kim F., Pieper, Lisa A., Fieder, Juergen, Gamer, Martin, Gorr, Ingo, Schulz, Patrick, Bradl, Harald
Publicado 2017

Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain

por Bauer, Joschka, Mathias, Sven, Kube, Sebastian, Otte, Kerstin, Garidel, Patrick, Gamer, Martin, Blech, Michaela, Fischer, Simon, Karow-Zwick, Anne R
Publicado 2020

Loss of a newly discovered microRNA in Chinese hamster ovary cells leads to upregulation of N‐glycolylneuraminic acid sialylation on monoclonal antibodies

por Fischer, Simon, Mathias, Sven, Stadermann, Anna, Yang, Shumin, Schmieder, Valerie, Zeh, Nikolas, Schmidt, Nicoletta, Richter, Patrick, Wright, Sara, Zimmermann, Eike, Ley, Yan, van der Meer, Julia, Hartsch, Thomas, Bernloehr, Christian, Otte, Kerstin, Bradl, Harald, Gamer, Martin, Schulz, Patrick
Publicado 2022