Outer Retinal Cell Replacement: Putting the Pieces Together

por Ludwig, Allison L., Gamm, David M.
Publicado 2021

Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level

por Udry, Florian, Decembrini, Sarah, Gamm, David M., Déglon, Nicole, Kostic, Corinne, Arsenijevic, Yvan
Publicado 2020

Necrotizing myositis in a rectus muscle arising in the setting of long-standing Langerhans cell histiocystosis and recent dabrafenib treatment

por van Landingham, Suzanne W., Puccetti, Diane, Potter, Heather, Gamm, David, Diamond, Eli L., Lucarelli, Mark J.
Publicado 2020

Generation of a rod-specific NRL reporter line in human pluripotent stem cells

por Phillips, M. Joseph, Capowski, Elizabeth E., Petersen, Andrew, Jansen, Alex D., Barlow, Katherine, Edwards, Kimberly L., Gamm, David M.
Publicado 2018

Retinal Ganglion Cell Diversity and Subtype Specification from Human Pluripotent Stem Cells

por Langer, Kirstin B., Ohlemacher, Sarah K., Phillips, M. Joseph, Fligor, Clarisse M., Jiang, Peng, Gamm, David M., Meyer, Jason S.
Publicado 2018

Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection

por Steyer, Benjamin, Bu, Qian, Cory, Evan, Jiang, Keer, Duong, Stella, Sinha, Divya, Steltzer, Stephanie, Gamm, David, Chang, Qiang, Saha, Krishanu
Publicado 2018

Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures

por Ludwig, Allison L., Mayerl, Steven J., Gao, Yu, Banghart, Mark, Bacig, Cole, Fernandez Zepeda, Maria A., Zhao, Xinyu, Gamm, David M.
Publicado 2023

β2–Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression

por Lavine, Jeremy A., Farnoodian, Mitra, Wang, Shoujian, Darjatmoko, Soesiawati R., Wright, Lynda S., Gamm, David M., Ip, Michael S., Sorenson, Christine M., Sheibani, Nader
Publicado 2017

VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures

por Wright, Lynda S., Pinilla, Isabel, Saha, Jishnu, Clermont, Joshua M., Lien, Jessica S., Borys, Katarzyna D., Capowski, Elizabeth E., Phillips, M. Joseph, Gamm, David M.
Publicado 2015

Ultrathin micromolded 3D scaffolds for high-density photoreceptor layer reconstruction

por Lee, In-Kyu, Ludwig, Allison L., Phillips, M. Joseph, Lee, Juhwan, Xie, Ruosen, Sajdak, Benjamin S., Jager, Lindsey D., Gong, Shaoqin, Gamm, David M., Ma, Zhenqiang
Publicado 2021

Protection of Visual Functions by Human Neural Progenitors in a Rat Model of Retinal Disease

por Gamm, David M., Wang, Shaomei, Lu, Bin, Girman, Sergei, Holmes, Toby, Bischoff, Nicholas, Shearer, Rebecca L., Sauvé, Yves, Capowski, Elizabeth, Svendsen, Clive N., Lund, Raymond D.
Publicado 2007

Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa

por Mayerl, Steven J., Bajgai, Simona, Ludwig, Allison L., Jager, Lindsey D., Williams, Brittany N., Bacig, Cole, Stoddard, Christopher, Sinha, Divya, Philpot, Benjamin D., Gamm, David M.
Publicado 2022

A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing

por Barone, Francesca, Amaral, Juan, Bunea, Irina, Farnoodian, Mitra, Gupta, Rohan, Gupta, Rishabh, Baker, Dara, Phillips, M. Joseph, Blanch, Richard J., Maminishkis, Arvydas, Gamm, David M., Bharti, Kapil
Publicado 2023

Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae

por Lakowski, Jörn, Welby, Emily, Budinger, Dimitri, Di Marco, Fabiana, Di Foggia, Valentina, Bainbridge, James W.B., Wallace, Kyle, Gamm, David M., Ali, Robin R., Sowden, Jane C.
Publicado 2018

Micromolded honeycomb scaffold design to support the generation of a bilayered RPE and photoreceptor cell construct

por Lee, In-Kyu, Xie, Ruosen, Luz-Madrigal, Agustin, Min, Seunghwan, Zhu, Jingcheng, Jin, Jiahe, Edwards, Kimberly L., Phillips, M. Joseph, Ludwig, Allison L., Gamm, David M., Gong, Shaoqin, Ma, Zhenqiang
Publicado 2023

Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin

por Galloway, Chad A., Dalvi, Sonal, Shadforth, Audra M. A., Suzuki, Shuko, Wilson, Molly, Kuai, David, Hashim, Ali, MacDonald, Leslie A., Gamm, David M., Harkin, Damien G., Singh, Ruchira
Publicado 2018

Generation of three dimensional retinal tissue with functional photoreceptors from human iPSCs

por Zhong, Xiufeng, Gutierrez, Christian, Xue, Tian, Hampton, Christopher, Vergara, M. Natalia, Cao, Li-Hui, Peters, Ann, Park, Tea-Soon, Zambidis, Elias T., Meyer, Jason S., Gamm, David M., Yau, King-Wai, Canto-Soler, M. Valeria
Publicado 2014

Investigating cone photoreceptor development using patient-derived NRL null retinal organoids

por Kallman, Alyssa, Capowski, Elizabeth E., Wang, Jie, Kaushik, Aniruddha M., Jansen, Alex D., Edwards, Kimberly L., Chen, Liben, Berlinicke, Cynthia A., Joseph Phillips, M., Pierce, Eric A., Qian, Jiang, Wang, Tza-Huei, Gamm, David M., Zack, Donald J.
Publicado 2020

Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

por Ripolles-Garcia, Ana, Dolgova, Natalia, Phillips, M. Joseph, Savina, Svetlana, Ludwig, Allison L., Stuedemann, Sara A., Nlebedum, Uchenna, Wolfe, John H., Garden, Oliver A., Maminishkis, Arvydas, Amaral, Juan, Bharti, Kapil, Gamm, David M., Aguirre, Gustavo D., Beltran, William A.
Publicado 2022

CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids

por Wahlin, Karl J., Cheng, Jie, Jurlina, Shawna L., Jones, Melissa K., Dash, Nicholas R., Ogata, Anna, Kibria, Nawal, Ray, Sunayan, Eldred, Kiara C., Kim, Catherine, Heng, Jacob S., Phillips, Jenny, Johnston, Robert J., Gamm, David M., Berlinicke, Cynthia, Zack, Donald J.
Publicado 2021