Programmed cell death in Leishmania: biochemical evidence and role in parasite infectivity

por Gannavaram, Sreenivas, Debrabant, Alain
Publicado 2012

Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection

por Ismail, Nevien, Kaul, Amit, Bhattacharya, Parna, Gannavaram, Sreenivas, Nakhasi, Hira L.
Publicado 2017

Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani

por Gannavaram, Sreenivas, Sharma, Paresh, Duncan, Robert C., Salotra, Poonam, Nakhasi, Hira L.
Publicado 2011

Deletion of Ubiquitin Fold Modifier Protein Ufm1 Processing Peptidase Ufsp in L. donovani Abolishes Ufm1 Processing and Alters Pathogenesis

por Gannavaram, Sreenivas, Davey, Sonya, Lakhal-Naouar, Ines, Duncan, Robert, Nakhasi, Hira L.
Publicado 2014

Biomarkers of Safety and Immune Protection for Genetically Modified Live Attenuated Leishmania Vaccines Against Visceral Leishmaniasis – Discovery and Implications

por Gannavaram, Sreenivas, Dey, Ranadhir, Avishek, Kumar, Selvapandiyan, Angamuthu, Salotra, Poonam, Nakhasi, Hira L.
Publicado 2014

Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory Molecules

por Gannavaram, Sreenivas, Bhattacharya, Parna, Ismail, Nevien, Kaul, Amit, Singh, Rakesh, Nakhasi, Hira L.
Publicado 2016

miR-21 Expression Determines the Early Vaccine Immunity Induced by LdCen(−/−) Immunization

por Gannavaram, Sreenivas, Bhattacharya, Parna, Siddiqui, Abid, Ismail, Nevien, Madhavan, Subha, Nakhasi, Hira L.
Publicado 2019

Identification and Characterization of Genes Involved in Leishmania Pathogenesis: The Potential for Drug Target Selection

por Duncan, Robert, Gannavaram, Sreenivas, Dey, Ranadhir, Debrabant, Alain, Lakhal-Naouar, Ines, Nakhasi, Hira L.
Publicado 2011

Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization

por Gannavaram, Sreenivas, Torcivia, John, Gasparyan, Lusine, Kaul, Amit, Ismail, Nevien, Simonyan, Vahan, Nakhasi, Hira L.
Publicado 2017

Centrin-Deleted Leishmania donovani Parasites Help CD4(+) T Cells to Acquire Th1 Phenotype and Multi-Functionality Through Downregulation of CD200–CD200R Immune Inhibitory Axis

por Singh, Rakesh K., Gannavaram, Sreenivas, Ismail, Nevien, Kaul, Amit, Gedda, Mallikarjuna Rao, Nakhasi, Hira L.
Publicado 2018

Immunity to Visceral Leishmaniasis Using Genetically Defined Live-Attenuated Parasites

por Selvapandiyan, Angamuthu, Dey, Ranadhir, Gannavaram, Sreenivas, Lakhal-Naouar, Ines, Duncan, Robert, Salotra, Poonam, Nakhasi, Hira L.
Publicado 2012

Field-Deployable Treatments For Leishmaniasis: Intrinsic Challenges, Recent Developments and Next Steps

por Pacheco-Fernandez, Thalia, Markle, Hannah, Verma, Chaitenya, Huston, Ryan, Gannavaram, Sreenivas, Nakhasi, Hira L, Satoskar, Abhay R
Publicado 2023

Revival of Leishmanization and Leishmanin

por Pacheco-Fernandez, Thalia, Volpedo, Greta, Gannavaram, Sreenivas, Bhattacharya, Parna, Dey, Ranadhir, Satoskar, Abhay, Matlashewski, Greg, Nakhasi, Hira L.
Publicado 2021

Toll-like Receptor-9 (TLR-9) Signaling Is Crucial for Inducing Protective Immunity following Immunization with Genetically Modified Live Attenuated Leishmania Parasites

por Bhattacharya, Parna, Gannavaram, Sreenivas, Ismail, Nevien, Saxena, Ankit, Dagur, Pradeep K., Akue, Adovi, KuKuruga, Mark, Nakhasi, Hira L.
Publicado 2023

Determinants of Innate Immunity in Visceral Leishmaniasis and Their Implication in Vaccine Development

por Volpedo, Greta, Pacheco-Fernandez, Thalia, Bhattacharya, Parna, Oljuskin, Timur, Dey, Ranadhir, Gannavaram, Sreenivas, Satoskar, Abhay R., Nakhasi, Hira L.
Publicado 2021

The History of Live Attenuated Centrin Gene-Deleted Leishmania Vaccine Candidates

por Volpedo, Greta, Bhattacharya, Parna, Gannavaram, Sreenivas, Pacheco-Fernandez, Thalia, Oljuskin, Timur, Dey, Ranadhir, Satoskar, Abhay R., Nakhasi, Hira L.
Publicado 2022

Interfacing of Science, Medicine and Law: The Stem Cell Patent Controversy in the United States and the European Union

por Davey, Sonya, Davey, Neil, Gu, Qian, Xu, Na, Vatsa, Rajet, Devalaraja, Samir, Harris, Paul, Gannavaram, Sreenivas, Dave, Raj, Chakrabarty, Ananda
Publicado 2015

Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs

por Avishek, Kumar, Kaushal, Himanshu, Gannavaram, Sreenivas, Dey, Ranadhir, Selvapandiyan, Angamuthu, Ramesh, V., Negi, Narender Singh, Dubey, Uma S., Nakhasi, Hira L., Salotra, Poonam
Publicado 2016

Deletion of MIF gene from live attenuated LdCen(−/−) parasites enhances protective CD4(+) T cell immunity

por Fiuza, Jacqueline Araújo, Gannavaram, Sreenivas, Gaze, Soraya Torres, de Ornellas, Letícia Gambogi, Alves, Érica Alessandra, Ismail, Nevien, Nakhasi, Hira Lal, Correa-Oliveira, Rodrigo
Publicado 2023

Leishmania major centrin knock-out parasites reprogram tryptophan metabolism to induce a pro-inflammatory response

por Oljuskin, Timur, Azodi, Nazli, Volpedo, Greta, Bhattacharya, Parna, Markle, Hannah L., Hamano, Shinjiro, Matlashewski, Greg, Satoskar, Abhay R., Gannavaram, Sreenivas, Nakhasi, Hira L.
Publicado 2023