An RNA tertiary switch by modifying how helices are tethered

por Ganser, Laura R, Mustoe, Anthony M, Al-Hashimi, Hashim M
Publicado 2014

Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics

por Clay, Mary C., Ganser, Laura R., Merriman, Dawn K., Al-Hashimi, Hashim M.
Publicado 2017

Nucleation and dissolution mechanism underlying amyotrophic lateral sclerosis/frontotemporal lobar dementia-linked fused in sarcoma condensates

por Djaja, Nathalie A., Chang, Matthew T., Beinart, Freya R., Morris, Vivian M., Ganser, Laura R., Myong, Sua
Publicado 2023

Switch-like compaction of poly(ADP-ribose) upon cation binding

por Badiee, Mohsen, Kenet, Adam L., Ganser, Laura R., Paul, Tapas, Myong, Sua, Leung, Anthony K. L.
Publicado 2023

Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level

por Liao, Ting-Wei, Huang, Lin, Wilson, Timothy J, Ganser, Laura R, Lilley, David M J, Ha, Taekjip
Publicado 2023

High Performance Virtual Screening by Targeting a High-resolution RNA Dynamic Ensemble

por Ganser, Laura R., Lee, Janghyun, Rangadurai, Atul, Merriman, Dawn K., Kelly, Megan L., Kansal, Aman D., Sathyamoorthy, Bharathwaj, Al-Hashimi, Hashim M.
Publicado 2018

Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays

por Kelly, Megan L., Chu, Chia-Chieh, Shi, Honglue, Ganser, Laura R., Bogerd, Hal P., Huynh, Kelly, Hou, Yuze, Cullen, Bryan R., Al-Hashimi, Hashim M.
Publicado 2021

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

por Ma, X. Rosa, Prudencio, Mercedes, Koike, Yuka, Vatsavayai, Sarat C., Kim, Garam, Harbinski, Fred, Briner, Adam, Rodriguez, Caitlin M., Guo, Caiwei, Akiyama, Tetsuya, Schmidt, H. Broder, Cummings, Beryl B., Wyatt, David W., Kurylo, Katherine, Miller, Georgiana, Mekhoubad, Shila, Sallee, Nathan, Mekonnen, Gemechu, Ganser, Laura, Rubien, Jack D., Jansen-West, Karen, Cook, Casey N., Pickles, Sarah, Oskarsson, Björn, Graff-Radford, Neill R., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Dickson, Dennis W., Shorter, James, Myong, Sua, Green, Eric M., Seeley, William W., Petrucelli, Leonard, Gitler, Aaron D.
Publicado 2022