Mitochondrial response to nutrient availability and its role in metabolic disease

por Gao, Arwen W, Cantó, Carles, Houtkooper, Riekelt H
Publicado 2014

Identification of key pathways and metabolic fingerprints of longevity in C. elegans

por Gao, Arwen W., Smith, Reuben L., van Weeghel, Michel, Kamble, Rashmi, Janssens, Georges E., Houtkooper, Riekelt H.
Publicado 2018

Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation

por Li, Terytty Yang, Wang, Qi, Gao, Arwen W., Li, Xiaoxu, Sun, Yu, Mottis, Adrienne, Shong, Minho, Auwerx, Johan
Publicado 2023

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

por Li, Terytty Yang, Gao, Arwen W., Li, Xiaoxu, Li, Hao, Liu, Yasmine J., Lalou, Amelia, Neelagandan, Nagammal, Naef, Felix, Schoonjans, Kristina, Auwerx, Johan
Publicado 2022

Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels

por Gao, Arwen W., Sterken, Mark G., uit de Bos, Jelmi, van Creij, Jelle, Kamble, Rashmi, Snoek, Basten L., Kammenga, Jan E., Houtkooper, Riekelt H.
Publicado 2018

Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

por Liu, Yasmine J., Janssens, Georges E., McIntyre, Rebecca L., Molenaars, Marte, Kamble, Rashmi, Gao, Arwen W., Jongejan, Aldo, van Weeghel, Michel, MacInnes, Alyson W., Houtkooper, Riekelt H.
Publicado 2019

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

por Li, Terytty Yang, Sleiman, Maroun Bou, Li, Hao, Gao, Arwen W., Mottis, Adrienne, Bachmann, Alexis Maximilien, El Alam, Gaby, Li, Xiaoxu, Goeminne, Ludger J. E., Schoonjans, Kristina, Auwerx, Johan
Publicado 2021

Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains

por Gao, Arwen W., El Alam, Gaby, Lalou, Amélia, Li, Terytty Yang, Molenaars, Marte, Zhu, Yunyun, Overmyer, Katherine A., Shishkova, Evgenia, Hof, Kevin, Bou Sleiman, Maroun, Houtkooper, Riekelt H., Coon, Joshua J., Auwerx, Johan
Publicado 2022

Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans

por Liu, Yasmine J., Gao, Arwen W., Smith, Reuben L., Janssens, Georges E., Panneman, Daan M., Jongejan, Aldo, van Weeghel, Michel, Vaz, Frédéric M., Silvestrini, Melissa J., Lapierre, Louis R., MacInnes, Alyson W., Houtkooper, Riekelt H.
Publicado 2022

Identifying gene function and module connections by the integration of multispecies expression compendia

por Li, Hao, Rukina, Daria, David, Fabrice P.A., Li, Terytty Yang, Oh, Chang-Myung, Gao, Arwen W., Katsyuba, Elena, Bou Sleiman, Maroun, Komljenovic, Andrea, Huang, Qingyao, Williams, Robert W., Robinson-Rechavi, Marc, Schoonjans, Kristina, Morgenthaler, Stephan, Auwerx, Johan
Publicado 2019

A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

por Gao, Arwen W., Chatzispyrou, Iliana A., Kamble, Rashmi, Liu, Yasmine J., Herzog, Katharina, Smith, Reuben L., van Lenthe, Henk, Vervaart, Martin A. T., van Cruchten, Arno, Luyf, Angela C., van Kampen, Antoine, Pras-Raves, Mia L., Vaz, Frédéric M., Houtkooper, Riekelt H.
Publicado 2017

Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation

por Molenaars, Marte, Schomakers, Bauke V., Elfrink, Hyung L., Gao, Arwen W., Vervaart, Martin A. T., Pras-Raves, Mia L., Luyf, Angela C., Smith, Reuben L., Sterken, Mark G., Kammenga, Jan E., van Kampen, Antoine H. C., Janssens, Georges E., Vaz, Frédéric M., van Weeghel, Michel, Houtkooper, Riekelt H.
Publicado 2021

Modeling Meets Metabolomics—The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism Caenorhabditis elegans

por Witting, Michael, Hastings, Janna, Rodriguez, Nicolas, Joshi, Chintan J., Hattwell, Jake P. N., Ebert, Paul R., van Weeghel, Michel, Gao, Arwen W., Wakelam, Michael J. O., Houtkooper, Riekelt H., Mains, Abraham, Le Novère, Nicolas, Sadykoff, Sean, Schroeder, Frank, Lewis, Nathan E., Schirra, Horst-Joachim, Kaleta, Christoph, Casanueva, Olivia
Publicado 2018